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NAT15

N(alpha)-acetyltransferase 60, NatF catalytic subunit

Histone acetyltransferase localized in the Golgi apparatus that mediates acetylation of free histone H4, thereby facilitating nucleosome assembly. Has a preference for free histone H4 'Lys-20'(H4K20ac), 'Lys-79'(H4K79ac) and 'Lys-91' (H4K91ac). Also displays alpha (N-terminal) acetyltransferase activity towards a range of N-terminal sequences including those starting with Met-Lys, Met-Val, Met-Ala and Met-Met. Required for normal chromosomal segregation during anaphase.

Gene Name:	N(alpha)-acetyltransferase 60, NatF catalytic subunit
Synonyms:	NAA60, HAT4, NAT15, NatF catalytic subunit, N-acetyltransferase 15, N-alpha-acetyltransferase 60
Target Sequences:	NM_024845 NP_079121.1 Q9H7X0

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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