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NAPSA / NAPA / Napsin A

napsin A aspartic peptidase

The activation peptides of aspartic proteinases plays role as inhibitors of the active site. These peptide segments, or pro-parts, are deemed important for correct folding, targeting, and control of the activation of aspartic proteinase zymogens. The pronapsin A gene is expressed predominantly in lung and kidney. Its translation product is predicted to be a fully functional, glycosylated aspartic proteinase precursor containing an RGD motif and an additional 18 residues at its C-terminus.

Gene Name:	napsin A aspartic peptidase
Family/Subfamily:	Protease , Aspartic A1
Synonyms:	NAPSA, Asp 4, ASP4, Aspartyl protease 4, Kdap, NAP1, Napsin A aspartic peptidase, Napsin-1, KAP, TA01/TA02, Napsin A, Napsin-A, SNAPA, NAP 1, Pronapsin A
Target Sequences:	NM_004851 NP_004842.1 O96009

Publications (2)

Human tissue distribution of TA02, which is homologous with a new type of aspartic proteinase, napsin A. Hirano T, Auer G, Maeda M, Hagiwara Y, Okada S, Ohira T, Okuzawa K, Fujioka K, Franzn B, Hibi N, Seito T, Ebihara Y, Kato H. Japanese journal of cancer research : Gann. 2000 91:1015-21. [PubMed:11050472]

Usefulness of TA02 (napsin A) to distinguish primary lung adenocarcinoma from metastatic lung adenocarcinoma. Hirano T, Gong Y, Yoshida K, Kato Y, Yashima K, Maeda M, Nakagawa A, Fujioka K, Ohira T, Ikeda N, Ebihara Y, Auer G, Kato H. Lung cancer (Amsterdam, Netherlands). 2003 41:155-62. [PubMed:12871778]

73 Antibodies 4 ELISA Kits 7 Proteins

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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