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NAPRT

Nicotinate Phosphoribosyltransferase Domain Containing 1

Nicotinic acid (NA; niacin) is converted by nicotinic acid phosphoribosyltransferase (NAPRT; EC 2.4.2.11) to NA mononucleotide (NaMN), which is then converted to NA adenine dinucleotide (NaAD), and finally to nicotinamide adenine dinucleotide (NAD), which serves as a coenzyme in cellular redox reactions and is an essential component of a variety of processes in cellular metabolism including response to stress (Hara et al., 2007).

Gene Name: Nicotinate Phosphoribosyltransferase Domain Containing 1
Synonyms: NAPRT, FHA-HIT-interacting protein, NAPRTase, NAPRT1, PP3856, FHIP
Target Sequences: AF258565 AAG23768.1 Q6XQN6

Publications (1)

1
Novel NAPRT specific antibody identifies small cell lung cancer and neuronal cancers as promising clinical indications for a NAMPT inhibitor/niacin co-administration strategy. Cole J, Guiot MC, Gravel M, Bernier C, Shore GC, Roulston A. Oncotarget. 2017 September;8:77846-77859. (Human) [Full Text Article] [PubMed:29100430] [PMC:PMC5652819] Related Antibodies: LS-C139287.

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Products
Antibodies (21)
Primary (21)
NAPRT (21)
Human (21)
Mouse (12)
Rat (7)
Bovine (8)
Chimpanzee (3)
Gibbon (6)
Guinea pig (4)
Hamster (8)
Horse (4)
Monkey (8)
Rabbit (4)
Xenopus (4)
Zebrafish (4)
IHC (4)
WB (21)
ELISA (9)
IF (1)
IP (1)
rabbit (19)
mouse (2)
IgG (9)
IgG2a (1)
IgG2a,k (1)
monoclonal mc (2)
polyclonal pc (19)
4A9 (1)
AP Conjugated (1)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
Unconjugated (11)
aa156-205 (4)
aa401-450 (4)
C-Terminus (1)
aa74-100 (1)
No (20)
Yes (1)
NAPRT Antibody - Western blot of NAPRT1 expression in transfected 293T cell line by NAPRT1 monoclonal antibody (M01), clone 4A9.
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NAPRT Mouse anti-Human Monoclonal (4A9) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$413
NAPRT Antibody - 1:100 staining human lymph carcinoma tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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NAPRT Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100 µl/$369; 200 µl/$411
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NAPRT Mouse anti-Human Monoclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$351
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NAPRT Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µl/$390; 200 µl/$413
NAPRT Antibody - Western blot All lanes: NAPRT antibody at 4 µg/ml Lane 1: HepG2 whole cell lysate Lane 2: Mouse liver tissue Lane 3: Mouse kidney tissue Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 58, 61, 57 kDa Observed band size: 57 kDa
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NAPRT Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
50 µg/$284; 100 µg/$348
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NAPRT Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA, WB
HRP Conjugated
50 µg/$284; 100 µg/$348
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NAPRT Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
50 µg/$284; 100 µg/$348
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NAPRT Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
50 µg/$284; 100 µg/$348
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NAPRT Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IP, WB
Unconjugated
100 µg/$321
NAPRT Antibody - NAPRT1 antibody Western Blot of Mouse Kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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NAPRT Rabbit anti-Mouse Polyclonal (aa156-205) Antibody
Xenopus, Rat, Hamster, Mouse, Bovine, Human, Monkey
WB
Unconjugated
100 µl/$414
NAPRT Antibody - NAPRT1 antibody Western Blot of Mouse Kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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NAPRT Rabbit anti-Mouse Polyclonal (aa156-205) (HRP) Antibody
Xenopus, Rat, Hamster, Mouse, Bovine, Human, Monkey, Gibbon
WB
HRP Conjugated
100 µl/$459
NAPRT Antibody - NAPRT1 antibody Western Blot of Mouse Kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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NAPRT Rabbit anti-Mouse Polyclonal (aa156-205) (Biotin) Antibody
Xenopus, Rat, Hamster, Mouse, Bovine, Human, Monkey, Gibbon
WB
Biotin Conjugated
100 µl/$459
NAPRT Antibody - NAPRT1 antibody Western Blot of Mouse Kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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NAPRT Rabbit anti-Mouse Polyclonal (aa156-205) (FITC) Antibody
Xenopus, Rat, Hamster, Mouse, Bovine, Human, Monkey, Gibbon
WB
FITC Conjugated
100 µl/$459
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NAPRT Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
60 µl/$280; 120 µl/$343; 200 µl/$451
NAPRT Antibody - NAPRT1 Antibody western blot of HepG2 cell line lysates (35 ug/lane). The NAPRT1 antibody detected the NAPRT1 protein (arrow).
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NAPRT Rabbit anti-Human Polyclonal (aa74-100) Antibody
Human
WB
Unconjugated
400 µl/$376
NAPRT Antibody - Western blot analysis of extracts of various cell lines, using NAPRT Antibody at 1:3000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 30s.
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NAPRT Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$253; 50 µl/$279; 100 µl/$333; 200 µl/$429
NAPRT Antibody - NAPRT1 antibody Western blot of Jurkat Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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NAPRT Rabbit anti-Human Polyclonal (aa401-450) Antibody
Zebrafish, Horse, Hamster, Rabbit, Mouse, Guinea pig, Bovine, Human, Monkey
WB
Unconjugated
100 µl/$414
NAPRT Antibody - NAPRT1 antibody Western blot of Jurkat Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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NAPRT Rabbit anti-Human Polyclonal (aa401-450) (HRP) Antibody
Zebrafish, Horse, Rabbit, Mouse, Guinea pig, Bovine, Hamster, Human, Monkey, Gibbon, Chimpanzee
WB
HRP Conjugated
100 µl/$459
NAPRT Antibody - NAPRT1 antibody Western blot of Jurkat Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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NAPRT Rabbit anti-Human Polyclonal (aa401-450) (Biotin) Antibody
Zebrafish, Horse, Rabbit, Mouse, Guinea pig, Bovine, Hamster, Human, Monkey, Gibbon, Chimpanzee
WB
Biotin Conjugated
100 µl/$459
NAPRT Antibody - NAPRT1 antibody Western blot of Jurkat Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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NAPRT Rabbit anti-Human Polyclonal (aa401-450) (FITC) Antibody
Zebrafish, Horse, Rabbit, Mouse, Guinea pig, Bovine, Hamster, Human, Monkey, Gibbon, Chimpanzee
WB
FITC Conjugated
100 µl/$459
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NAPRT Rabbit anti-Human Polyclonal (AP) Antibody
Human
WB
AP Conjugated
100 µl/$333; 200 µl/$429
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).