NAF-1 / CISD2

CDGSH iron sulfur domain 2

Regulator of autophagy that contributes to antagonize BECN1-mediated cellular autophagy at the endoplasmic reticulum. Participates in the interaction of BCL2 with BECN1 and is required for BCL2-mediated depression of endoplasmic reticulum Ca2+ stores during autophagy. Contributes to BIK-initiated autophagy, while it is not involved in BIK-dependent activation of caspases. Involved in life span control, probably via its function as regulator of autophagy.

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Products

Proteins (2)

Type

Recombinant (2)

Target

NAF-1 / CISD2 (2)

Publications

No (2)

Tag

GST (1)

His, N-Terminal (1)

Species

Human (2)

Source

E. coli (1)

Wheat Germ Extract (1)

Purification

Purified (1)

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Human NAF-1 / CISD2 Protein (Recombinant GST) (Full Length) - LS-G37525

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

41.7 kDa

Price:

10 µg/$479; 25 µg/$670

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Human NAF-1 / CISD2 Protein (Recombinant His, N-Terminal) - LS-G144281

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

15.1 kDa

Price:

50 µg/$419

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