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NAE1 / APPBP1
NEDD8 activating enzyme E1 subunit 1
Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Necessary for cell cycle progression through the S-M checkpoint. Overexpression of NAE1 causes apoptosis through deregulation of NEDD8 conjugation.
| Gene Name: | NEDD8 activating enzyme E1 subunit 1 |
| Synonyms: | NAE1, A-116A10.1, APPBP1, HPP1, Proto-oncogene protein 1, APP-BP1, Ula-1, Protooncogene protein 1 |
| Target Sequences: | NM_003905 NP_003896.1 Q13564 |
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Products
Antibodies
(53)
Type
Primary
(53)
Target
NAE1 / APPBP1
(53)
Reactivity
Human
(52)
Mouse
(9)
Rat
(8)
Application
IHC
(18)
IHC-P
(5)
WB
(53)
ELISA
(22)
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(1)
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(1)
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rabbit
(35)
mouse
(18)
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(17)
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(6)
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(2)
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(6)
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(4)
Clonality
monoclonal mc
(18)
polyclonal pc
(35)
Clone
4E8-H3
(1)
OTI1A10
(2)
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(2)
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(2)
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(2)
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(1)
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(4)
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(2)
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(5)
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(6)
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(1)
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(1)
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(5)
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(5)
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(4)
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(28)
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aa1-274
(12)
aa172-200
(7)
aa430-459
(7)
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(4)
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(1)
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(1)
Publications
No
(53)
NAE1 / APPBP1 Mouse anti-Human Monoclonal (aa1-274) (OTI1E10) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
NAE1 / APPBP1 Mouse anti-Human Monoclonal (aa1-274) (Carrier-free) (OTI1E10) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
NAE1 / APPBP1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
NAE1 / APPBP1 Rabbit anti-Human Polyclonal (aa172-200) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
NAE1 / APPBP1 Rabbit anti-Human Polyclonal (aa172-200) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
NAE1 / APPBP1 Rabbit anti-Human Polyclonal (aa172-200) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
NAE1 / APPBP1 Rabbit anti-Human Polyclonal (aa172-200) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
NAE1 / APPBP1 Rabbit anti-Human Polyclonal (aa172-200) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
NAE1 / APPBP1 Rabbit anti-Human Polyclonal (aa172-200) (Azide-free) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
NAE1 / APPBP1 Rabbit anti-Human Polyclonal (aa430-459) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
NAE1 / APPBP1 Rabbit anti-Human Polyclonal (aa430-459) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
NAE1 / APPBP1 Rabbit anti-Human Polyclonal (aa430-459) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
NAE1 / APPBP1 Rabbit anti-Human Polyclonal (aa430-459) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
NAE1 / APPBP1 Rabbit anti-Human Polyclonal (aa430-459) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
NAE1 / APPBP1 Rabbit anti-Human Polyclonal (aa430-459) (Azide-free) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
NAE1 / APPBP1 Rabbit anti-Human Polyclonal (aa452-482) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
NAE1 / APPBP1 Rabbit anti-Human Polyclonal (aa172-200) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
NAE1 / APPBP1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IP, WB
Unconjugated
100 µg/$331
NAE1 / APPBP1 Mouse anti-Human Monoclonal (4E8-H3) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$705
NAE1 / APPBP1 Mouse anti-Human Monoclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
100 µl/$904
NAE1 / APPBP1 Mouse anti-Human Monoclonal (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
100 µl/$904
NAE1 / APPBP1 Mouse anti-Human Monoclonal (PE) Antibody
Human
ELISA, WB
PE Conjugated
100 µl/$904
NAE1 / APPBP1 Mouse anti-Human Monoclonal (APC) Antibody
Human
ELISA, WB
APC Conjugated
100 µl/$904
NAE1 / APPBP1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
NAE1 / APPBP1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
Viewing 26-50
of 53
product results
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