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N6AMT1

N-6 adenine-specific DNA methyltransferase 1 (putative)

Heterodimeric methyltransferase that catalyzes N5-methylation of ETF1 on 'Gln-185', using S-adenosyl L-methionine as methyl donor. ETF1 needs to be complexed to ERF3 in its GTP-bound form to be efficiently methylated. May play a role in the modulation of arsenic-induced toxicity. May be involved in the conversion of monomethylarsonous acid (3+) into the less toxic dimethylarsonic acid.

Gene Name: N-6 adenine-specific DNA methyltransferase 1 (putative)
Synonyms: N6AMT1, M.HsaHemK2P, HEMK2, N6AMT, C21orf127, MTQ2, N6-DNA-methyltransferase, PRED28
Target Sequences: NM_013240 NP_037372.4 Q9Y5N5

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Products
Proteins (7)
Over-Expression Lysate (2)
Recombinant (5)
N6AMT1 (7)
No (7)
GST (1)
GST, N-terminus (2)
His (2)
Myc-DDK (Flag) (2)
Human (6)
293T Cells (1)
E. coli (3)
HEK 293 Cells (1)
Wheat Germ Extract (2)
Purified (4)
N6AMT1 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
N6AMT1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
19.6 kDa
20 µg/$150
N6AMT1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
19.6 kDa
100 µg/$494
N6AMT1 Protein
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E. coli
His
20 µg/$298; 100 µg/$454; 10 µg/$261; 50 µg/$361; 250 µg/$739; 500 µg/$1,177
N6AMT1 Protein - 12.5% SDS-PAGE of human HEMK2 stained with Coomassie Blue
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Wheat Germ Extract
GST
46.2 kDa
10 µg/$479; 25 µg/$670
N6AMT1 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
GST, N-terminus
1 mg/$1,355; 100 µg/$420; 20 µg/$323
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E. coli
His
21.2 kDa
100 µg/$502
Viewing 1-7 of 7 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).