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MYST2 / HBO1

K(lysine) acetyltransferase 7

Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Through chromatin acetylation it may regulate DNA replication and act as a coactivator of TP53-dependent transcription. Specifically represses AR-mediated transcription.

Gene Name:	K(lysine) acetyltransferase 7
Synonyms:	KAT7, Histone acetyltransferase KAT7, HBO1, Lysine acetyltransferase 7, HBOA, MYST-2, MYST2, K(lysine) acetyltransferase 7, ZC2HC7
Target Sequences:	NM_007067 NP_008998.1 O95251

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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