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MYST1

K(lysine) acetyltransferase 8

Histone acetyltransferase which may be involved in transcriptional activation. May influence the function of ATM. As part of the MSL complex it is involved in acetylation of nucleosomal histone H4 producing specifically H4K16ac. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. That activity is less specific than the one of the MSL complex. Can also acetylate TP53/p53 at 'Lys-120'.

Gene Name:	K(lysine) acetyltransferase 8
Synonyms:	KAT8, Histone acetyltransferase KAT8, HMOF, MOF, K(lysine) acetyltransferase 8, Lysine acetyltransferase 8, MYST1, ZC2HC8, MYST-1
Target Sequences:	NM_032188 NP_115564.2 Q9H7Z6

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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