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MYOD / MYOD1

myogenic differentiation 1

Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. Together with MYF5 and MYOG, co-occupies muscle-specific gene promoter core region during myogenesis. Induces fibroblasts to differentiate into myoblasts. Interacts with and is inhibited by the twist protein. This interaction probably involves the basic domains of both proteins.

Gene Name:	myogenic differentiation 1
Synonyms:	MYOD1, BHLHc1, Myogenic differentiation 1, Myf-3, MYOD, Myogenic factor 3, PUM, MYF3
Target Sequences:	NM_002478 NP_002469.2 P15172

Publications (2)

Candidate Heterotaxy Gene FGFR4 Is Essential for Patterning of the Left-Right Organizer in Xenopus. Sempou E, Lakhani OA, Amalraj S, Khokha MK. Frontiers in physiology. 2018 December;9:1705. [Full Text Article] [PubMed:30564136] [PMC:PMC6288790] Related Antibodies: LS-C143580.

Functional skeletal muscle model derived from SOD1-mutant ALS patient iPSCs recapitulates hallmarks of disease progression. Agnes Badu-Mensah, Xiufang Guo, Christopher W McAleer, John W Rumsey, James J Hickman. Scientific reports. 2020 August;10:14302. [Full Text Article] [PubMed:32868812] [PMC:PMC7459299] Related Antibodies: LS-C263888.

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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