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MYO9B

myosin IXB

MYO9B is a member of the myosin family of actin-based molecular motor heavy chain proteins. The protein represents an unconventional myosin; it should not be confused with the conventional non-muscle myosin-9 (MYH9). The protein has four IQ motifs located in the neck domain that bind calmodulin, which serves as a light chain. The protein complex has a single-headed structure and exhibits processive movement on actin filaments toward the minus-end. The protein also has rho-GTPase activity. Polymorphisms in this gene are associated with celiac disease and ulcerative colitis susceptibility. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Name: myosin IXB
Synonyms: MYO9B, CELIAC4, Myosin IXB, Myosin-IXb, Unconventional myosin-IXb, Unconventional myosin IXb, Unconventional myosin-9b, MYR5
Target Sequences: NM_004145 NP_004136.2 Q13459

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Proteins (1)
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MYO9B (1)
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GST, N-terminus (1)
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Wheat Germ Extract (1)
MYO9B Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).