MYO7A / Myosin-VIIa

myosin VIIA

Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails bind to membranous compartments, which are then moved relative to actin filaments. In the retina, plays an important role in the renewal of the outer photoreceptor disks. Plays an important role in the distribution and migration of retinal pigment epithelial (RPE) melanosomes and phagosomes, and in the regulation of opsin transport in retinal photoreceptors. In the inner ear, plays an important role in differentiation, morphogenesis and organization of cochlear hair cell bundles. Involved in hair-cell vesicle trafficking of aminoglycosides, which are known to induce ototoxicity (By similarity). Motor protein that is a part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal hearing.

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Proteins (2)

Type

Recombinant (2)

Target

MYO7A / Myosin-VIIa (2)

Publications

No (2)

Tag

6His-SUMO, N-terminus (1)

GST, N-terminus (1)

Species

Human (2)

Source

E. coli (1)

Wheat Germ Extract (1)

Purification

Purified (1)

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Human MYO7A / Myosin-VIIa Protein (Recombinant GST, N-terminus) (aa2118-2213) - LS-G59329

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human MYO7A / Myosin-VIIa Protein (Recombinant 6His-SUMO, N-terminus) (aa838-968) - LS-G56727

Source:

E. coli

Tag:

6His-SUMO, N-terminus

Price:

1 mg/$1,679; 100 µg/$500; 20 µg/$364

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