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MYO3A

myosin IIIA

MYO3A belongs to the myosin superfamily. Myosins are actin-dependent motor proteins and are categorized into conventional myosins (class II) and unconventional myosins (classes I and III through XV) based on their variable C-terminal cargo-binding domains. Class III myosins, such as this one, have a kinase domain N-terminal to the conserved N-terminal motor domains and are expressed in photoreceptors. The protein encoded by this gene plays an important role in hearing in humans. Three different recessive, loss of function mutations in the encoded protein have been shown to cause nonsyndromic progressive hearing loss. Expression of this gene is highly restricted, with the strongest expression in retina and cochlea.

Gene Name: myosin IIIA
Family/Subfamily: Protein Kinase , NinaC
Synonyms: MYO3A, DFNB30, Myosin IIIA, Myosin-IIIa
Target Sequences: NM_017433 NP_059129.3 Q8NEV4

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Proteins (2)
Recombinant (2)
MYO3A (2)
No (2)
GST (1)
GST, N-terminus (1)
Human (2)
Wheat Germ Extract (2)
Purified (1)
MYO3A Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
MYO3A Protein - 12.5% SDS-PAGE of human MYO3A stained with Coomassie Blue
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Wheat Germ Extract
GST
54 kDa
10 µg/$479; 25 µg/$670
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).