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MYLIP / IDOL

Myosin Regulatory Light Chain Interacting Protein

E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of myosin regulatory light chain (MRLC), LDLR, VLDLR and LRP8. Activity depends on E2 enzymes of the UBE2D family. Proteasomal degradation of MRLC leads to inhibit neurite outgrowth in presence of NGF by counteracting the stabilization of MRLC by saposin-like protein (CNPY2/MSAP) and reducing CNPY2-stimulated neurite outgrowth. Acts as a sterol-dependent inhibitor of cellular cholesterol uptake by mediating ubiquitination and subsequent degradation of LDLR.

Gene Name: Myosin Regulatory Light Chain Interacting Protein
Synonyms: MYLIP
Target Sequences: NM_013262 NP_037394.2 Q8WY64

☰ Filters
Products
Antibodies (20)
Primary (20)
MYLIP / IDOL (20)
Human (20)
Mouse (14)
Rat (7)
Bat (3)
Bovine (1)
Chimpanzee (3)
Monkey (1)
Pig (3)
IHC (14)
IHC-P (4)
WB (19)
Flo (6)
ELISA (9)
IF (1)
Peptide-ELISA (2)
rabbit (18)
mouse (2)
IgG (13)
IgG1 (2)
monoclonal mc (2)
polyclonal pc (18)
OTI3A2 (2)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (2)
Carrier-free (1)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (1)
Unconjugated (12)
aa360-409 (4)
aa127-385 (2)
Internal (1)
aa161-210 (1)
No (20)
MYLIP / IDOL Antibody - MYLIP antibody Western blot of SK-MEL-2 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MYLIP / IDOL Rabbit anti-Human Polyclonal (aa360-409) Antibody
Human
WB
Unconjugated
100 µl/$424
MYLIP / IDOL Antibody - MYLIP antibody Western blot of SK-MEL-2 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MYLIP / IDOL Rabbit anti-Human Polyclonal (aa360-409) (HRP) Antibody
Mouse, Rat, Pig, Bat, Chimpanzee, Human
WB
HRP Conjugated
100 µl/$469
MYLIP / IDOL Antibody - MYLIP antibody Western blot of SK-MEL-2 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MYLIP / IDOL Rabbit anti-Human Polyclonal (aa360-409) (Biotin) Antibody
Mouse, Rat, Pig, Bat, Chimpanzee, Human
WB
Biotin Conjugated
100 µl/$469
MYLIP / IDOL Antibody - MYLIP antibody Western blot of SK-MEL-2 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MYLIP / IDOL Rabbit anti-Human Polyclonal (aa360-409) (FITC) Antibody
Mouse, Rat, Pig, Bat, Chimpanzee, Human
WB
FITC Conjugated
100 µl/$469
MYLIP / IDOL Antibody - Immunohistochemistry analysis of paraffin-embedded human brain tissue, using MYLIP Antibody. The picture on the right is blocked with the synthesized peptide.
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MYLIP / IDOL Rabbit anti-Human Polyclonal (aa161-210) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
MYLIP / IDOL Antibody - 1:100 staining human liver carcinoma tissues by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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MYLIP / IDOL Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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MYLIP / IDOL Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, Flo, IHC, WB
Unconjugated
200 µl/$734
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MYLIP / IDOL Rabbit anti-Human Polyclonal (Biotin) Antibody
Mouse, Human
ELISA, Flo, IHC, WB
Biotin Conjugated
200 µl/$952
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MYLIP / IDOL Rabbit anti-Human Polyclonal (FITC) Antibody
Mouse, Human
ELISA, Flo, IHC, WB
FITC Conjugated
200 µl/$952
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MYLIP / IDOL Rabbit anti-Human Polyclonal (PE) Antibody
Mouse, Human
ELISA, Flo, IHC, WB
PE Conjugated
200 µl/$952
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MYLIP / IDOL Rabbit anti-Human Polyclonal (APC) Antibody
Mouse, Human
ELISA, Flo, IHC, WB
APC Conjugated
200 µl/$952
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MYLIP / IDOL Rabbit anti-Human Polyclonal (Azide-free) (HRP) Antibody
Mouse, Human
ELISA, Flo, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
MYLIP / IDOL Antibody - Immunohistochemistry of paraffin-embedded human heart tissue at dilution of 1:100
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MYLIP / IDOL Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
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MYLIP / IDOL Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$341
MYLIP / IDOL Antibody - Immunohistochemistry of paraffin-embedded human heart tissue at dilution of 1:100
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MYLIP / IDOL Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
MYLIP / IDOL Antibody - Immunohistochemical analysis of IDOL staining in human heart formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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MYLIP / IDOL Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Bovine, Human, Monkey
IHC, IHC-P, WB
Unconjugated
100 µl/$299
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MYLIP / IDOL Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
MYLIP / IDOL Antibody - Immunohistochemistry of paraffin-embedded human prostate tissue.
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MYLIP / IDOL Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
MYLIP / IDOL Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY MYLIP. (Right lane) cDNA for 48 hrs and lysed
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MYLIP / IDOL Mouse anti-Human Monoclonal (aa127-385) (OTI3A2) Antibody
Human
WB
Unconjugated
100 µl/$434
MYLIP / IDOL Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY MYLIP. (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates. (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-MYLIP. (1:2000)
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MYLIP / IDOL Mouse anti-Human Monoclonal (aa127-385) (Carrier-free) (OTI3A2) Antibody
Human
WB
Unconjugated, Carrier-free
100 µg/$511
Viewing 1-20 of 20 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).