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MYH7

myosin, heavy chain 7, cardiac muscle, beta

Muscle myosin is a hexameric protein containing 2 heavy chain subunits, 2 alkali light chain subunits, and 2 regulatory light chain subunits. This gene encodes the beta (or slow) heavy chain subunit of cardiac myosin. It is expressed predominantly in normal human ventricle. It is also expressed in skeletal muscle tissues rich in slow-twitch type I muscle fibers. Changes in the relative abundance of this protein and the alpha (or fast) heavy subunit of cardiac myosin correlate with the contractile velocity of cardiac muscle. Its expression is also altered during thyroid hormone depletion and hemodynamic overloading. Mutations in this gene are associated with familial hypertrophic cardiomyopathy, myosin storage myopathy, dilated cardiomyopathy, and Laing early-onset distal myopathy.

Gene Name: myosin, heavy chain 7, cardiac muscle, beta
Synonyms: MYH7, Beta-myosin heavy chain, MYHCB, Myosin heavy chain (AA 1-96), MPD1, Myhc-slow, Myopathy, distal 1, Myosin heavy chain 7, MyHC-beta, Myosin-7, CMD1S, CMH1, SPMD, SPMM
Target Sequences: M58018 P12883 P12883

Publications (3)

1
Characterization of cytoskeleton features and maturation status of cultured human iPSC-derived cardiomyocytes. Christian Zuppinger, George Gibbons, Priyanka Dutta-Passecker, Adrian Segiser, Henriette Most, Thomas M Suter. European journal of histochemistry : EJH. 2017 Jun;61:2763. [Full Text Article] [PubMed:28735524] [PMC:PMC5484009] Related Antibodies: LS-C312448.
2
3D Co-culture of hiPSC-Derived Cardiomyocytes With Cardiac Fibroblasts Improves Tissue-Like Features of Cardiac Spheroids. Philippe Beauchamp, Christopher B Jackson, Lijo Cherian Ozhathil, Irina Agarkova, Cristi L Galindo, Douglas B Sawyer, Thomas M Suter, Christian Zuppinger. Frontiers in molecular biosciences. 2020 Feb;7:14. [Full Text Article] [PubMed:32118040] [PMC:PMC7033479] Related Antibodies: LS-C312448.
3
Ascribing novel functions to the sarcomeric protein, myosin binding protein H (MyBPH) in cardiac sarcomere contraction. Mouton J, Loos B, Moolman-Smook JC, Kinnear CJ. Experimental cell research. Feb;331:338-51. [Full Text Article] [PubMed:25449695] Related Antibodies: LS-B5888.

☰ Filters
Antibodies (31)
ELISA Kits (10)
Proteins (2)
Competitive EIA (1)
Custom (5)
Primary (31)
Recombinant (2)
Sandwich (4)
MYH7 (43)
Human (33)
Mouse (18)
Rat (9)
Bat (3)
Bovine (4)
Chimpanzee (3)
Crab-eating macaque (1)
Dog (4)
Gibbon (3)
Guinea pig (3)
Hamster (3)
Horse (3)
Monkey (3)
Pig (4)
Rabbit (4)
IHC (11)
IHC-P (9)
WB (26)
ELISA (8)
IF (1)
IP (1)
Peptide-ELISA (1)
rabbit (30)
mouse (1)
Product Group
IHCPlus (2)
IgG (16)
IgG1 (1)
monoclonal mc (1)
polyclonal pc (30)
IML-64 (1)
96-Well Strip Plate (10)
APC (1)
APC Conjugated (2)
Azide-free (1)
Biotin Conjugated (4)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (2)
Unconjugated (13)
aa1268-1516 (8)
aa185-211 (7)
aa1251-1300 (4)
aa1-76 (1)
No (41)
Yes (2)
Cell Lysates (1)
Plasma (4)
Serum (4)
Tissue Homogenates (3)
GST, N-terminus (1)
His (1)
Human (2)
E. coli (1)
Wheat Germ Extract (1)
MYH7 Antibody - Anti-MYH7 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MYH7 Rabbit anti-Mouse Polyclonal (aa1251-1300) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
MYH7 Antibody - Anti-MYH7 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MYH7 Rabbit anti-Mouse Polyclonal (aa1251-1300) (HRP) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Rat, Hamster, Chimpanzee, Gibbon, Human, Monkey
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
MYH7 Antibody - Anti-MYH7 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MYH7 Rabbit anti-Mouse Polyclonal (aa1251-1300) (Biotin) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Rat, Hamster, Chimpanzee, Gibbon, Human, Monkey
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
MYH7 Antibody - Anti-MYH7 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MYH7 Rabbit anti-Mouse Polyclonal (aa1251-1300) (FITC) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Rat, Hamster, Chimpanzee, Gibbon, Human, Monkey
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
MYH7 Antibody - WB of MYH7 antibody. All lanes: Anti-Myosin(slow) at 0.5ug/ml. Lane 1: Rat Skeletal Muscle Tissue Lysate at 40ug. Lane 2: Mouse Skeletal Muscle Tissue Lysate at 40ug. Predicted bind size: 200KD. Observed bind size: 200KD.
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MYH7 Mouse anti-Human Monoclonal (IML-64) Antibody
Rabbit, Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
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MYH7 Rabbit anti-Human Polyclonal (aa1-76) Antibody
Human
ELISA
Unconjugated
100 µl/$450
MYH7 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$834
MYH7 Antibody - Skeletal muscle, human: Formalin-Fixed, Paraffin-Embedded (FFPE), at a dilution of 1:100.
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MYH7 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
MYH7 Antibody - MYH7 Antibody western blot of mouse spleen tissue lysates (35 ug/lane). The MYH7 antibody detected the MYH7 protein (arrow).
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MYH7 Rabbit anti-Human Polyclonal (aa185-211) Antibody
Mouse, Human
WB
Unconjugated
400 µl/$393
MYH7 Antibody - 1:100 staining mouse muscle tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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MYH7 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
MYH7 Antibody - Western blot of recombinant MYH7.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MYH7 Rabbit anti-Human Polyclonal (aa1268-1516) Antibody
Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
MYH7 Antibody - Western blot of recombinant MYH7.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MYH7 Rabbit anti-Human Polyclonal (aa1268-1516) (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$319; 200 µl/$365; 500 µl/$519; 1 ml/$596; 2 ml/$824; 5 ml/$1,348
MYH7 Antibody - Western blot of recombinant MYH7.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MYH7 Rabbit anti-Human Polyclonal (aa1268-1516) (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$348; 200 µl/$407; 500 µl/$605; 1 ml/$755; 2 ml/$993; 5 ml/$1,716
MYH7 Protein - Recombinant Myosin Heavy Chain 7, Cardiac Muscle, Beta By SDS-PAGE
Select
E. coli
His
30.5 kDa
10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176
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MYH7 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$341
MYH7 Antibody - Immunohistochemistry image at a dilution of 1:800 and staining in paraffin-embedded human heart tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0) . Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4 °C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
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MYH7 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
MYH7 Antibody - Immunochemical staining of human MYH7 in cynomolgus heart with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.
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MYH7 Rabbit anti-Human Polyclonal Antibody
Human, Crab-eating macaque
IHC-P, IP, WB
Unconjugated
100 µl/$412
MYH7 Antibody
Select
MYH7 Rabbit anti-Human Polyclonal Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$286; 100 µl/$321
Select
MYH7 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
Select
MYH7 Rabbit anti-Human Polyclonal (aa185-211) Antibody
Mouse, Human
WB
Unconjugated
200 µl/$734
Select
MYH7 Rabbit anti-Human Polyclonal (aa185-211) (Biotin) Antibody
Mouse, Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
MYH7 Rabbit anti-Human Polyclonal (aa185-211) (FITC) Antibody
Mouse, Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
MYH7 Rabbit anti-Human Polyclonal (aa185-211) (APC) Antibody
Mouse, Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
MYH7 Rabbit anti-Human Polyclonal (aa185-211) (PE) Antibody
Mouse, Human
ELISA, WB
PE Conjugated
200 µl/$952
Select
MYH7 Rabbit anti-Human Polyclonal (aa185-211) (Azide-free) (HRP) Antibody
Mouse, Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
Viewing 1-25 of 43 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).