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MYBPC2

myosin binding protein C, fast type

MYBPC2 is a member of the myosin-binding protein C family. This family includes the fast-, slow- and cardiac-type isoforms, each of which is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. The protein encoded by this locus is referred to as the fast-type isoform. Mutations in the related but distinct genes encoding the slow-type and cardiac-type isoforms have been associated with distal arthrogryposis, type 1 and hypertrophic cardiomyopathy, respectively.

Gene Name: myosin binding protein C, fast type
Synonyms: MYBPC2, MYBPCF, Fast MyBP-C, MYBPC
Target Sequences: NM_004533 NP_004524.3 Q14324

Publications (1)

1
Low-Intensity Training and the C5a Complement Antagonist NOX-D21 Rescue the mdx Phenotype through Modulation of Inflammation. Hyzewicz J, Tanihata J, Kuraoka M, Nitahara-Kasahara Y, Beylier T, Ruegg UT, Vater A, Takeda S. The American journal of pathology. 2017 May;187:1147-1161. (Human) [Full Text Article] [PubMed:28315675] Related Antibodies: LS-C101947.

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Proteins (5)
Over-Expression Lysate (2)
Recombinant (3)
MYBPC2 (5)
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6His, N-terminus (1)
His (1)
Myc-DDK (Flag) (3)
Human (4)
293T Cells (1)
E. coli (1)
HEK 293 Cells (2)
Yeast (1)
Purified (1)
MYBPC2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
127.9 kDa
100 µg/$710
MYBPC2 Protein
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Yeast
His
47.5 kD
100 µg/$446; 20 µg/$336; 1 mg/$1,460
MYBPC2 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
6His, N-terminus
1 mg/$1,355; 100 µg/$420; 20 µg/$323
MYBPC2 Protein - Purified recombinant protein MYBPC2 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
127.9 kDa
20 µg/$1,107
MYBPC2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
127.9 kDa
20 µg/$215
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).