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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Research Areas
Cell Cycle Pathways
Protein Family And Group
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MYB / c-Myb

v-myb avian myeloblastosis viral oncogene homolog

MYB / c-Myb is a transcription factor that is a member of the MYB family of transcription factor genes. The protein contains three domains, an N-terminal DNA-binding domain, a central transcriptional activation domain and a C-terminal domain involved in transcriptional repression. This protein plays an essential role in the regulation of hematopoiesis and may play a role in tumorigenesis. Alternative splicing results in multiple transcript variants.

Gene Name: v-myb avian myeloblastosis viral oncogene homolog
Synonyms: MYB, C-myb_CDS, C-myb8B_CDS, C-myb protein (140 AA), C-myb10A_CDS, C-myb13A_CDS, Efg, Transcriptional activator Myb, C-myb, C-myb14A_CDS, Cmyb, Proto-oncogene c-Myb
Target Sequences: NM_005375 NP_005366.2 P10242

Publications (4)

1
Significant inverse correlation of microRNA-150/MYB and microRNA-222/p27 in myelodysplastic syndrome. Hussein K, Theophile K, Bsche G, Schlegelberger B, Ghring G, Kreipe H, Bock O. Leukemia research. 2010 34:328-34. (IHC) [PubMed:19615744]
2
The Expression of c-Myb Correlates with the Levels of Rhabdomyosarcoma-specific Marker Myogenin. Kaspar P, Zikova M, Bartunek P, Sterba J, Strnad H, Kren L, Sedlacek R. Scientific reports. 2015 5:15090. (IHC; Mouse) [Full Text Article] [PubMed:26462877] [PMC:PMC4604482] Related Antibodies: LS-B5315.
3
Aberrant expression of AID and AID activators of NF-?B and PAX5 is irrelevant to EBV-associated gastric cancers, but is associated with carcinogenesis in certain EBV-non-associated gastric cancers. Mohri T, Nagata K, Kuwamoto S, Matsushita M, Sugihara H, Kato M, Horie Y, Murakami I, Hayashi K. Oncology letters. 2017 13:4133-4140. (ICC; Human) [Full Text Article] [PubMed:28588701] [PMC:PMC5452920]
4
Higher Expression of Activation-induced Cytidine Deaminase Is Significantly Associated with Merkel Cell Polyomavirus-negative Merkel Cell Carcinomas. Matsushita M, Iwasaki T, Nonaka D, Kuwamoto S, Nagata K, Kato M, Kitamura Y, Hayashi K. Yonago acta medica. 2017 September;60:145-153. [Full Text Article] [PubMed:28959124] [PMC:PMC5611468]
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Viewing 1-25 of 106 items
MYB / c-Myb Antibody - Anti-c-Myb antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
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Rabbit Polyclonal (IgG) to Human MYB / c-Myb
Mouse, Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50µl   1mg/ml   $425.00
MYB / c-Myb Antibody - Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Rabbit Polyclonal to Human MYB / c-Myb
Mouse, Bovine, Rat, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
50µl   1mg/ml   $425.00
MYB / c-Myb Antibody - Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Rabbit Polyclonal (IgG) to Human MYB / c-Myb
Chicken, Zebrafish, Pig, Horse, Bat, Rat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey
IHC, IHC-P, WB
Unconjugated
100µl   0.5mg/ml   $485.00
MYB / c-Myb Antibody - Anti-c-Myb antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.
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Goat Polyclonal to Human MYB / c-Myb
Rabbit, Dog, Pig, Horse, Bat, Human, Monkey
IHC, IHC-P
Unconjugated
50µg   0.5mg/ml   $425.00
MYB / c-Myb Antibody - Western blot of c-Myb antibody
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Rabbit Polyclonal (IgG) to Human MYB / c-Myb
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
50µl   1mg/ml   $235.00; 100µl   1mg/ml   $265.00; 200µl   1mg/ml   $335.00
MYB / c-Myb Antibody - IHC of MYB (R6) pAb in paraffin-embedded human breast carcinoma tissue.
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Rabbit Polyclonal to Human MYB / c-Myb
Mouse, Human
IF, IHC, IHC-P, WB
Unconjugated
100µl   $345.00
MYB / c-Myb Antibody - Formalin-fixed, paraffin-embedded human seminoma stained with peroxidase-conjugate and AEC chromogen. Note cytoplasmic staining of tumor cells.  This image was taken for the unmodified form of this product. Other forms have not been tested.
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Mouse Monoclonal [clone 4E3] (IgG2a) to Human MYB / c-Myb
Human
IHC, IHC-P, WB
Unconjugated
0.1ml   $280.00; 0.5ml   $555.00; 1ml   $925.00
MYB / c-Myb Antibody - Formalin-fixed, paraffin-embedded human seminoma stained with peroxidase-conjugate and AEC chromogen. Note cytoplasmic staining of tumor cells.  This image was taken for the unmodified form of this product. Other forms have not been tested.
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Mouse Monoclonal [clone 4E3] (IgG2a) to Human MYB / c-Myb
Human
IHC, IHC-P, WB
Unconjugated, Azide-free
0.1ml   $610.00; 0.2ml   $1,015.00
MYB / c-Myb Antibody - Anti-C-Myb Antibody - Western Blot. Western blot of affinity purified anti-C-Myb antibody in Cos7 cell lysates: Lane 1: vector; Lane 2: transfected with c-myb, no treatment; Lane 3: transfected with c-Myb and heat stress-treated (incubation at 42oC for 30 minutes) to induce c-Myb modification. Lane 3 shows detection of bands at 75, 98, and 125kD corresponding to overexpressed c-Myb (arrows): wild-type, with one attached SUMO molecule, and with two attached SUMO molecules, respectively. Nitrocellulose 0.45mum membrane was blocked for 1 hr at RT in 10% BLOTTO in PBS. The primary antibody was used at 1:500. Personal communication, J. Bies, NCI NIH, Bethesda.
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Rabbit Polyclonal (IgG) to Mouse MYB / c-Myb
Mouse
ELISA, WB
Unconjugated
100µg   1.51mg/ml   $425.00
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Mouse Monoclonal [clone MYB286] (IgG1,k) to Human MYB / c-Myb
Human
Flo
Unconjugated
20µg   0.2mg/ml   $295.00; 100µg   0.2mg/ml   $465.00
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Mouse Monoclonal (IgG2a) to Human MYB / c-Myb
Human
WB
Unconjugated
250µl   $435.00
MYB / c-Myb Antibody - 1:100 staining human Testis tissue by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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Rabbit Polyclonal (IgG) to Human MYB / c-Myb
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
100µl   1mg/ml   $325.00; 200µl   1mg/ml   $375.00
MYB / c-Myb Antibody - Peptide - + Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using MYB (Ab-12) antibody.
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Rabbit Polyclonal (IgG) to Human MYB / c-Myb
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
100µg   $305.00
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Rabbit Polyclonal (IgG) to Human MYB / c-Myb
Mouse, Human
ELISA, IHC, IHC-P, WB
Unconjugated
200µl   $590.00
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Rabbit Polyclonal (IgG) to Human MYB / c-Myb
Mouse, Human
ELISA, IHC, IHC-P, WB
Biotin Conjugated
200µl   $740.00
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Rabbit Polyclonal (IgG) to Human MYB / c-Myb
Mouse, Human
ELISA, IHC, IHC-P, WB
FITC Conjugated
200µl   $740.00
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Rabbit Polyclonal (IgG) to Human MYB / c-Myb
Mouse, Human
ELISA, IHC, IHC-P, WB
HRP Conjugated, Azide-free
200µl   $740.00
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Rabbit Polyclonal (IgG) to Human MYB / c-Myb
Mouse, Human
ELISA, IHC, IHC-P, WB
APC Conjugated
200µl   $740.00
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Rabbit Polyclonal (IgG) to Human MYB / c-Myb
Mouse, Human
ELISA, IHC, IHC-P, WB
AP Conjugated
200µl   $740.00
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Rabbit Polyclonal (IgG) to Human MYB / c-Myb
Mouse, Human
ELISA, IHC, IHC-P, WB
PE Conjugated
200µl   $740.00
MYB / c-Myb Antibody - Goat anti-MYB / c-myb Antibody (2µg/ml) staining of paraffin embedded Human Kidney. Steamed antigen retrieval with citrate buffer pH 6, HRP-staining.
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Goat Polyclonal to Human MYB / c-Myb
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
100µg   0.5mg/ml   $405.00
MYB / c-Myb Antibody - Immunohistochemistry analysis of paraffin-embedded human heart, using MYB (Phospho-Ser12) Antibody. The picture on the right is blocked with the phospho peptide.
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Rabbit Polyclonal (IgG) to Human MYB / c-Myb
Mouse, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50µl   1mg/ml   $265.00; 100µl   1mg/ml   $325.00
Select
Rabbit Polyclonal (IgG) to Human MYB / c-Myb
Human
ELISA, IHC, WB
Unconjugated
200µl   $590.00
Select
Rabbit Polyclonal (IgG) to Human MYB / c-Myb
Mouse, Human
ELISA, IHC, WB
Unconjugated
50µl   1mg/ml   $235.00; 100µl   1mg/ml   $265.00; 200µl   1mg/ml   $335.00
MYB / c-Myb Antibody - Western blot of recombinant MYB / c-Myb.
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Rabbit Polyclonal to Human MYB / c-Myb
Mouse, Human
ICC, IP, WB
Unconjugated
100µl   0.5mg/ml   $255.00; 200µl   0.5mg/ml   $295.00; 500µl   0.5mg/ml   $425.00; 1ml   0.5mg/ml   $495.00

Viewing 1-25 of 106 items


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).