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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

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Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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MYB / c-Myb

v-myb avian myeloblastosis viral oncogene homolog

MYB / c-Myb is a transcription factor that is a member of the MYB family of transcription factor genes. The protein contains three domains, an N-terminal DNA-binding domain, a central transcriptional activation domain and a C-terminal domain involved in transcriptional repression. This protein plays an essential role in the regulation of hematopoiesis and may play a role in tumorigenesis. Alternative splicing results in multiple transcript variants.

Gene Name: v-myb avian myeloblastosis viral oncogene homolog
Synonyms: MYB, C-myb_CDS, C-myb8B_CDS, C-myb protein (140 AA), C-myb10A_CDS, C-myb13A_CDS, Efg, Transcriptional activator Myb, C-myb, C-myb14A_CDS, Cmyb, Proto-oncogene c-Myb
Target Sequences: NM_005375 NP_005366.2 P10242

Publications (4)

1
Significant inverse correlation of microRNA-150/MYB and microRNA-222/p27 in myelodysplastic syndrome. Hussein K, Theophile K, Bsche G, Schlegelberger B, Ghring G, Kreipe H, Bock O. Leukemia research. 2010 34:328-34. (IHC) [PubMed:19615744]
2
The Expression of c-Myb Correlates with the Levels of Rhabdomyosarcoma-specific Marker Myogenin. Kaspar P, Zikova M, Bartunek P, Sterba J, Strnad H, Kren L, Sedlacek R. Scientific reports. 2015 5:15090. (IHC; Mouse) [Full Text Article] [PubMed:26462877] [PMC:PMC4604482] Related Antibodies: LS-B5315.
3
Aberrant expression of AID and AID activators of NF-?B and PAX5 is irrelevant to EBV-associated gastric cancers, but is associated with carcinogenesis in certain EBV-non-associated gastric cancers. Mohri T, Nagata K, Kuwamoto S, Matsushita M, Sugihara H, Kato M, Horie Y, Murakami I, Hayashi K. Oncology letters. 2017 13:4133-4140. (ICC; Human) [Full Text Article] [PubMed:28588701] [PMC:PMC5452920]
4
Higher Expression of Activation-induced Cytidine Deaminase Is Significantly Associated with Merkel Cell Polyomavirus-negative Merkel Cell Carcinomas. Matsushita M, Iwasaki T, Nonaka D, Kuwamoto S, Nagata K, Kato M, Kitamura Y, Hayashi K. Yonago acta medica. 2017 September;60:145-153. [Full Text Article] [PubMed:28959124] [PMC:PMC5611468]
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Filtered by: None
Target
MYB / c-Myb (106)
Reactivity
Human (92)
Mouse (64)
Rat (3)
Bat (5)
Bovine (5)
Chicken (4)
Chimpanzee (3)
Dog (3)
Gibbon (3)
Guinea pig (4)
Horse (6)
Monkey (6)
Pig (6)
Rabbit (5)
Xenopus (1)
Zebrafish (4)
Application
IHC (38)
IHC-P (23)
WB (88)
Flo (2)
ELISA (36)
ICC (2)
IF (6)
IP (16)
Peptide-ELISA (6)
Host
rabbit (76)
mouse (24)
goat (5)
sheep (1)
Isotype
IgG (41)
IgG1 (5)
IgG1,k (3)
IgG2a (9)
IgG2a,k (7)
Clonality
monoclonal mc (24)
polyclonal pc (82)
Clone
10A3 (1)
1279CT309.289 (1)
4E3 (2)
7C3 (1)
MYB286 (2)
Format
AP Conjugated (4)
APC (2)
APC Conjugated (5)
Azide-free (4)
Biotin Conjugated (9)
Cy3 Conjugated (2)
Cy7 Conjugated (2)
FITC Conjugated (9)
Gold Conjugated (1)
HRP Conjugated (9)
PE Conjugated (6)
Unconjugated (59)
Epitope
C-Terminus (14)
aa305-558 (8)
aa35-291 (8)
aa419-448 (8)
aa26-75 (4)
pSer532 (3)
1-80 aa (2)
470-550 aa (2)
aa1-50 (2)
aa119-135 (2)
Arg6 (1)
Ile526 (1)
Internal (1)
N-Terminus (1)
aa1-185 (1)
aa1-201 (1)
aa241-254 (1)
aa281-294 (1)
aa496-545 (1)
aa503-552 (1)
aa557-569 (1)
aa591-640 (1)
pSer12 (1)
pThr486 (1)
Publications
No (105)
Yes (1)
Showing 1-25 of 106 results

IHC-plus™ MYB / c-Myb Antibody (aa1-50) LS-B5315
Publications (1)
Publications (1)
Rabbit Polyclonal (IgG) to Human MYB / c-Myb
Mouse, Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50µl 1mg/ml  $425.00
Anti-c-Myb antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
Anti-c-Myb antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.

IHC-plus™ MYB / c-Myb Antibody (N-Terminus) LS-B14085
Rabbit Polyclonal to Human MYB / c-Myb
Mouse, Bovine, Rat, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
50µl 1mg/ml  $425.00
Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE)

MYB / c-Myb Antibody (clone 4E3) LS-C87830
Mouse Monoclonal [clone 4E3] (IgG2a) to Human MYB / c-Myb
Human
IHC, IHC-P, WB
Unconjugated
0.1ml  $280.00; 0.5ml  $555.00; 1ml  $925.00
Formalin-fixed, paraffin-embedded human seminoma stained with peroxidase-conjugate and AEC chromogen. Note cytoplasmic staining of tumor cells.  This image was taken for the unmodified form of this product. Other forms have not been tested.

MYB / c-Myb Antibody (clone 4E3, Azide-free) LS-C87831
Mouse Monoclonal [clone 4E3] (IgG2a) to Human MYB / c-Myb
Human
IHC, IHC-P, WB
Unconjugated, Azide-free
0.1ml  $610.00; 0.2ml  $1,015.00
Formalin-fixed, paraffin-embedded human seminoma stained with peroxidase-conjugate and AEC chromogen. Note cytoplasmic staining of tumor cells.  This image was taken for the unmodified form of this product. Other forms have not been tested.

MYB / c-Myb Antibody (Internal) LS-C153812
Rabbit Polyclonal (IgG) to Mouse MYB / c-Myb
Mouse
ELISA, WB
Unconjugated
100µg 1.51mg/ml  $425.00
Anti-C-Myb Antibody - Western Blot. Western blot of affinity purified anti-C-Myb antibody in Cos7 cell lysates: Lane 1: vector; Lane 2: transfected with c-myb, no treatment; Lane 3: transfected with c-Myb and heat stress-treated (incubation at 42oC for 30 minutes) to induce c-Myb modification. Lane 3 shows detection of bands at 75, 98, and 125kD corresponding to overexpressed c-Myb (arrows): wild-type, with one attached SUMO molecule, and with two attached SUMO molecules, respectively. Nitrocellulose 0.45mum membrane was blocked for 1 hr at RT in 10% BLOTTO in PBS. The primary antibody was used at 1:500. Personal communication, J. Bies, NCI NIH, Bethesda.

MYB / c-Myb Antibody (aa119-135, clone MYB286) LS-C391542
Mouse Monoclonal [clone MYB286] (IgG1,k) to Human MYB / c-Myb
Human
Flo
Unconjugated
20µg 0.2mg/ml  $295.00; 100µg 0.2mg/ml  $465.00

MYB / c-Myb Antibody LS-C9147
Mouse Monoclonal (IgG2a) to Human MYB / c-Myb
Human
WB
Unconjugated
250µl  $435.00

MYB / c-Myb Antibody (phospho-Ser532) LS-C800996
Rabbit Polyclonal (IgG) to Human MYB / c-Myb
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
100µl 1mg/ml  $325.00; 200µl 1mg/ml  $375.00
Immunohistochemistry Image
Immunofluorescence Image

MYB / c-Myb Antibody (1-80 aa) LS-C382785
Rabbit Polyclonal (IgG) to Human MYB / c-Myb
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
50µl 1mg/ml  $235.00; 100µl 1mg/ml  $265.00; 200µl 1mg/ml  $335.00
Western blot of c-Myb antibody

IHC-plus™ MYB / c-Myb Antibody (aa26-75) LS-B11880
Rabbit Polyclonal (IgG) to Human MYB / c-Myb
Chicken, Zebrafish, Pig, Horse, Bat, Rat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey
IHC, IHC-P, WB
Unconjugated
100µl  $485.00
Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.

MYB / c-Myb Antibody (Arg6) LS-C176431
Rabbit Polyclonal to Human MYB / c-Myb
Mouse, Human
IF, IHC, IHC-P, WB
Unconjugated
100µl  $345.00
IHC of MYB (R6) pAb in paraffin-embedded human breast carcinoma tissue.

IHC-plus™ MYB / c-Myb Antibody (aa241-254) LS-B5143
Goat Polyclonal to Human MYB / c-Myb
Rabbit, Dog, Pig, Horse, Bat, Human, Monkey
IHC, IHC-P
Unconjugated
50µg 0.5mg/ml  $425.00
Anti-c-Myb antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.
Anti-c-Myb antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.

MYB / c-Myb Antibody (C-Terminus) LS-C327951
Rabbit Polyclonal (IgG) to Human MYB / c-Myb
Mouse, Human
ELISA, IHC, IHC-P, WB
Unconjugated
200µl  $590.00

MYB / c-Myb Antibody (C-Terminus, Biotin) LS-C279754
Rabbit Polyclonal (IgG) to Human MYB / c-Myb
Mouse, Human
ELISA, IHC, IHC-P, WB
Biotin Conjugated
200µl  $740.00

MYB / c-Myb Antibody (C-Terminus, FITC) LS-C279756
Rabbit Polyclonal (IgG) to Human MYB / c-Myb
Mouse, Human
ELISA, IHC, IHC-P, WB
FITC Conjugated
200µl  $740.00

MYB / c-Myb Antibody (C-Terminus, APC) LS-C279755
Rabbit Polyclonal (IgG) to Human MYB / c-Myb
Mouse, Human
ELISA, IHC, IHC-P, WB
APC Conjugated
200µl  $740.00

MYB / c-Myb Antibody (C-Terminus, Azide-free, HRP) LS-C279757
Rabbit Polyclonal (IgG) to Human MYB / c-Myb
Mouse, Human
ELISA, IHC, IHC-P, WB
HRP Conjugated, Azide-free
200µl  $740.00

MYB / c-Myb Antibody (C-Terminus, AP) LS-C279753
Rabbit Polyclonal (IgG) to Human MYB / c-Myb
Mouse, Human
ELISA, IHC, IHC-P, WB
AP Conjugated
200µl  $740.00

MYB / c-Myb Antibody (C-Terminus, PE) LS-C279761
Rabbit Polyclonal (IgG) to Human MYB / c-Myb
Mouse, Human
ELISA, IHC, IHC-P, WB
PE Conjugated
200µl  $740.00

MYB / c-Myb Antibody (aa281-294) LS-C55135
Goat Polyclonal to Human MYB / c-Myb
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
100µg 0.5mg/ml  $405.00
Goat anti-MYB / c-myb Antibody (2µg/ml) staining of paraffin embedded Human Kidney. Steamed antigen retrieval with citrate buffer pH 6, HRP-staining.
Antibody (0.3 ug/ml) staining of Human Spleen lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

MYB / c-Myb Antibody (phospho-Ser12) LS-C199289
Rabbit Polyclonal (IgG) to Human MYB / c-Myb
Mouse, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50µl 1mg/ml  $265.00; 100µl 1mg/ml  $325.00
Immunohistochemistry analysis of paraffin-embedded human heart, using MYB (Phospho-Ser12) Antibody. The picture on the right is blocked with the phospho peptide.
Western blot analysis of lysates from HeLa cells treated with Hu 2nM 24h, using MYB (Phospho-Ser12) Antibody. The lane on the right is blocked with the phospho peptide.

MYB / c-Myb Antibody (1-80 aa) LS-C381253
Rabbit Polyclonal (IgG) to Human MYB / c-Myb
Mouse, Human
ELISA, IHC, WB
Unconjugated
50µl 1mg/ml  $235.00; 100µl 1mg/ml  $265.00; 200µl 1mg/ml  $335.00

MYB / c-Myb Antibody (aa419-448) LS-C323176
Rabbit Polyclonal (IgG) to Human MYB / c-Myb
Human
ELISA, IHC, WB
Unconjugated
200µl  $590.00

MYB / c-Myb Antibody (aa305-558) LS-C296997
Rabbit Polyclonal to Human MYB / c-Myb
Mouse, Human
ICC, IP, WB
Unconjugated
20µl 0.5mg/ml  $205.00; 100µl 0.5mg/ml  $255.00; 200µl 0.5mg/ml  $295.00; 1ml 0.5mg/ml  $495.00
Western blot of recombinant MYB / c-Myb.
Western Blot; Sample: Human Jurkat cell lysate; Primary Ab: 2µg/ml Rabbit Anti-Human MYB Antibody Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody

MYB / c-Myb Antibody (470-550 aa) LS-C382783
Rabbit Polyclonal (IgG) to Human MYB / c-Myb
Mouse, Human
ELISA, IHC, WB
Unconjugated
50µl 1mg/ml  $235.00; 100µl 1mg/ml  $265.00; 200µl 1mg/ml  $335.00
Western blot of c-Myb antibody
Showing 1-25 of 106 results

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For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).