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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Cell Cycle Pathways
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MURF1 / IRF

tripartite motif containing 63, E3 ubiquitin protein ligase

E3 ubiquitin ligase. Mediates the ubiquitination and subsequent proteasomal degradation of CKM, GMEB1 and HIBADH. Regulates the proteasomal degradation of muscle proteins under amino acid starvation, where muscle protein is catabolized to provide other organs with amino acids. Inhibits de novo skeletal muscle protein synthesis under amino acid starvation. Regulates proteasomal degradation of cardiac troponin I/TNNI3 and probably of other sarcomeric-associated proteins. May play a role in striated muscle atrophy and hypertrophy by regulating an anti-hypertrophic PKC-mediated signaling pathway. May regulate the organization of myofibrils through TTN in muscle cells.

Gene Name: tripartite motif containing 63, E3 ubiquitin protein ligase
Family/Subfamily: Tripartite Motif
Synonyms: TRIM63, Iris RING finger protein, MURF-1, MURF1, MuRF2, IRF, RING finger protein 28, RNF28, Tripartite motif-containing 63, Tripartite motif containing 63, SMRZ
Target Sequences: NM_032588 NP_115977.2 Q969Q1

☰ Filters
Viewing 1-4 of 4 items
MURF1 / IRF Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc + DDK
40.1 kDa
20µg   $195.00
MURF1 / IRF Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST,N-terminus
10µg   $425.00; 25µg   $590.00
MURF1 / IRF Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc + DDK
40.1 kDa
100µg   $365.00
MURF1 / IRF Protein - 12.5% SDS-PAGE of human TRIM63 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
66.6 kDa
10µg   $425.00; 25µg   $590.00

Viewing 1-4 of 4 items


If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).