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Involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture. Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation. Required for efficient DNA repair and cell survival following DNA damage.
Gene Name: | melanoma associated antigen (mutated) 1 |
Synonyms: | MUM1, EXPAND1, HSPC211, MUM-1, Protein expandere |
Target Sequences: | AAF36131.1 |
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