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MTRR

5-methyltetrahydrofolate-homocysteine methyltransferase reductase

Methionine is an essential amino acid required for protein synthesis and one-carbon metabolism. Its synthesis is catalyzed by the enzyme methionine synthase. Methionine synthase eventually becomes inactive due to the oxidation of its cob(I)alamin cofactor. The protein encoded by this gene regenerates a functional methionine synthase via reductive methylation. It is a member of the ferredoxin-NADP(+) reductase (FNR) family of electron transferases. Patients of the cbl-E complementation group of disorders of folate/cobalamin metabolism are defective in reductive activation of methionine synthase. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.

Gene Name: 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
Synonyms: MTRR, CblE, MSR, Methionine synthase reductase
Target Sequences: NM_024010 NP_076915.2

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Products
Proteins (5)
Over-Expression Lysate (2)
Recombinant (3)
MTRR (5)
No (5)
GST (1)
GST, N-terminus (1)
His (1)
Myc-DDK (Flag) (2)
Human (4)
293T Cells (1)
E. coli (1)
HEK 293 Cells (1)
Wheat Germ Extract (1)
Yeast (1)
MTRR Protein
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E. coli
GST
107.76 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
MTRR Protein
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Yeast
His
82.41 kD
100 µg/$446; 20 µg/$336; 1 mg/$1,460
MTRR Protein - 12.5% SDS-PAGE Stained with Coomassie Blue
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
MTRR Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
80.2 kDa
20 µg/$215
MTRR Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
80.2 kDa
100 µg/$710
Viewing 1-5 of 5 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).