MTMR3

myotubularin related protein 3

Myotubularin-related protein 3 (MTMR3), a myotubularin-related phosphatase, has been shown to contain the consensus active site of dual specificity protein phosphatases (DSPs) and to share inhibition and inactivation characteristics with other DSPs. Similar to other myotubularin-related proteins, MTMR3 has been shown to possess a SET (Suvar3-9, Enhancer of zeste, trithorax)-interacting domain (SID) which may mediate interactions with SET domains present in chromatin-organizing nuclear proteins. Additionally, MTMR3 has been shown to possess a double zinc finger (FYVE) domain at its C-terminus and to efficiently and specifically dephosphorylate phosphotidylinositol 3-phosphate (PtdIns3P) and PtdIns3,5P2 in vitro and in yeast. Thus, MTMR3 is believed to be associated with the phosphatidylinositol 3-kinase pathway, the cellular production of PtdIns5P and membrane trafficking. At least three mRNA isoforms have been hypothesized.

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Antibodies (4)

Proteins (1)

Type

Primary (4)

Recombinant (1)

Target

MTMR3 (5)

Reactivity

Human (4)

Application

WB (4)

ELISA (2)

Host

rabbit (3)

mouse (1)

Isotype

IgG (2)

IgG2a,k (1)

Clonality

monoclonal mc (1)

polyclonal pc (3)

Clone

1E11 (1)

Format

Unconjugated (4)

Publications

No (5)

Tag

GST, N-terminus (1)

Species

Human (1)

Source

Wheat Germ Extract (1)

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MTMR3 Antibody (clone 1E11) LS-C139357

Antibody:

MTMR3 Mouse anti-Human Monoclonal (1E11) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$423

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MTMR3 Antibody LS-C752639

Antibody:

MTMR3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$351

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MTMR3 Antibody LS-C497513

Antibody:

MTMR3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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MTMR3 Antibody LS-C667920

Antibody:

MTMR3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

50 µl/$286; 100 µl/$321

Select

Human MTMR3 Protein (Recombinant GST, N-terminus) (aa579-674) - LS-G60927

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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