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MTMR2

myotubularin related protein 2

Myotubularin-related protein 2 (MTMR2), a myotubularin-related phosphatase, has been shown to contain the consensus active site of dual specificity protein phosphatases (DSPs) and to share inhibition and inactivation characteristics with other DSPs. Similar to other myotubularin-related proteins, MTMR2 has been shown to possess a SET (Suvar3-9, Enhancer of zeste, trithorax)-interacting domain (SID) which may mediate interactions with SET domains present in chromatin-organizing nuclear proteins. Like myotubulin, MTMR2 has been shown to be highly specific for phosphatidylinositol 3-phosphatases as a substrate. Two alternatively spliced forms have been identified. MTMR2 has been identified as the gene responsible for Charcot-Marie-Tooth disease type 4B (CMT4B), an autosomal recessive demyelinating neuropathy.

Gene Name: myotubularin related protein 2
Family/Subfamily: Protein Phosphatase , Myotubularin-Related
Synonyms: MTMR2, CMT4B, KIAA1073, Myotubularin related protein 2, Myotubularin-related protein 2, CMT4B1
Target Sequences: NM_016156 NP_057240.3 Q13614

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Products
Proteins (10)
Over-Expression Lysate (5)
Recombinant (5)
MTMR2 (10)
No (10)
GST (1)
GST, N-terminus (1)
Myc-DDK (Flag) (8)
Human (8)
293T Cells (3)
HEK 293 Cells (5)
Wheat Germ Extract (2)
Purified (1)
MTMR2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
73.2 kDa
100 µg/$494
MTMR2 Protein - 12.5% SDS-PAGE of human MTMR2 stained with Coomassie Blue
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Wheat Germ Extract
GST
92.4 kDa
10 µg/$479; 25 µg/$670
MTMR2 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
MTMR2 Protein - Purified recombinant protein MTMR2 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
73.2 kDa
20 µg/$1,107
MTMR2 Protein - Purified recombinant protein MTMR2 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
65.8 kDa
20 µg/$1,107
MTMR2 Protein - Purified recombinant protein MTMR2 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
65.8 kDa
20 µg/$1,107
MTMR2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
73.2 kDa
20 µg/$150
MTMR2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
65.8 kDa
20 µg/$150
Select
293T Cells
Myc-DDK (Flag)
65.8 kDa
20 µg/$150
MTMR2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
65.8 kDa
100 µg/$494
Viewing 1-10 of 10 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).