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MTMR2

myotubularin related protein 2

Myotubularin-related protein 2 (MTMR2), a myotubularin-related phosphatase, has been shown to contain the consensus active site of dual specificity protein phosphatases (DSPs) and to share inhibition and inactivation characteristics with other DSPs. Similar to other myotubularin-related proteins, MTMR2 has been shown to possess a SET (Suvar3-9, Enhancer of zeste, trithorax)-interacting domain (SID) which may mediate interactions with SET domains present in chromatin-organizing nuclear proteins. Like myotubulin, MTMR2 has been shown to be highly specific for phosphatidylinositol 3-phosphatases as a substrate. Two alternatively spliced forms have been identified. MTMR2 has been identified as the gene responsible for Charcot-Marie-Tooth disease type 4B (CMT4B), an autosomal recessive demyelinating neuropathy.

Gene Name: myotubularin related protein 2
Family/Subfamily: Protein Phosphatase , Myotubularin-Related
Synonyms: MTMR2, CMT4B, KIAA1073, Myotubularin related protein 2, Myotubularin-related protein 2, CMT4B1
Target Sequences: NM_016156 NP_057240.3 Q13614

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Products
Antibodies (17)
Primary (17)
MTMR2 (17)
Human (17)
Mouse (3)
Rat (1)
IHC (1)
IHC-P (1)
WB (14)
Flo (6)
ELISA (3)
rabbit (9)
mouse (8)
IgG (7)
IgG1 (8)
monoclonal mc (8)
polyclonal pc (9)
OTI1F10 (2)
OTI1H8 (2)
OTI2D2 (2)
OTI5G5 (2)
Biotin Conjugated (1)
Carrier-free (4)
FITC Conjugated (1)
HRP Conjugated (1)
Unconjugated (14)
aa1-50 (1)
No (17)
MTMR2 Antibody - Immunohistochemistry image at a dilution of 1:400 and staining in paraffin-embedded human testis tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0) . Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4 °C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
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MTMR2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
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MTMR2 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
HRP Conjugated
50 µg/$294; 100 µg/$360
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MTMR2 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
Biotin Conjugated
50 µg/$294; 100 µg/$360
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MTMR2 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
FITC Conjugated
50 µg/$294; 100 µg/$360
MTMR2 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MTMR2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-MTMR2.
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MTMR2 Mouse anti-Human Monoclonal (OTI2D2) Antibody
Human
Flo, WB
Unconjugated
100 µl/$434
MTMR2 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MTMR2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-MTMR2.
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MTMR2 Mouse anti-Human Monoclonal (Carrier-free) (OTI2D2) Antibody
Human
Flo, WB
Unconjugated, Carrier-free
100 µg/$511
MTMR2 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MTMR2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-MTMR2.
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MTMR2 Mouse anti-Human Monoclonal (OTI1H8) Antibody
Human
Flo, WB
Unconjugated
100 µl/$434
MTMR2 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MTMR2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-MTMR2.
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MTMR2 Mouse anti-Human Monoclonal (Carrier-free) (OTI1H8) Antibody
Human
Flo, WB
Unconjugated, Carrier-free
100 µg/$511
MTMR2 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MTMR2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-MTMR2.
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MTMR2 Mouse anti-Human Monoclonal (OTI5G5) Antibody
Human
Flo, WB
Unconjugated
100 µl/$434
MTMR2 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MTMR2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-MTMR2.
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MTMR2 Mouse anti-Human Monoclonal (Carrier-free) (OTI5G5) Antibody
Human
Flo, WB
Unconjugated, Carrier-free
100 µg/$511
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MTMR2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
0.1 mg/$394
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MTMR2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$331
MTMR2 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MTMR2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-MTMR2.
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MTMR2 Mouse anti-Human Monoclonal (OTI1F10) Antibody
Human
WB
Unconjugated
100 µl/$434
MTMR2 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MTMR2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-MTMR2.
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MTMR2 Mouse anti-Human Monoclonal (Carrier-free) (OTI1F10) Antibody
Human
WB
Unconjugated, Carrier-free
100 µg/$511
MTMR2 Antibody - Western blot analysis of extracts of various cells.
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MTMR2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
MTMR2 Antibody
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MTMR2 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µl/$286; 100 µl/$321
MTMR2 Antibody - Detection of human and mouse MTMR2 by western blot. Samples: Whole cell lysate (50 µg) from HeLa, HEK293T, Jurkat, mouse TCMK-1, and mouse NIH 3T3 cells prepared using NETN lysis buffer. Antibodies: Affinity purified rabbit anti-MTMR2 antibody used for WB at 0.4 µg/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.
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MTMR2 Rabbit anti-Human Polyclonal (aa1-50) Antibody
Mouse, Human
WB
Unconjugated
10 µl/$295; 100 µl/$514
Viewing 1-17 of 17 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).