MTM1 / Myotubularin

myotubularin 1

Myotubularin (MTM1), a myotubularin-related phosphatase, has been shown to contain the consensus active site of dual specificity protein phosphatases (DSPs) and to share inhibition and inactivation characteristics with other DSPs in vitro and in vivo. MTM1 also has been shown to possess a SET-interacting domain (SID) which is unique to myotubularin-related proteins. SID has been shown to mediate interactions in vitro with SET (Suvar3-9, Enhancer of zeste, trithorax) domains in nuclear proteins implicated in chromatin organization. Recent studies have indicated that MTM1 is also a lipid phosphatase, acting on phosphatidylinositol 3-monophosphate, and may regulate the phosphatidylinositol 3-kinase (PI 3-kinase) pathway and membrane trafficking. Additionally, myotubularin has been implicated in the regulation of cell growth and the release of spermatids. MTM1 has been identified as the locus containing mutations responsible for X-linked myotubular myopathy (XLMTM), and more than 130 different mutations have been identified in the MTM1 gene worldwide.

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Antibodies (25)

ELISA Kits (4)

Proteins (4)

Type

Custom (2)

Over-Expression Lysate (2)

Primary (25)

Recombinant (2)

Sandwich (2)

Target

MTM1 / Myotubularin (33)

Reactivity

Human (24)

Mouse (20)

Rat (4)

Bovine (5)

Gibbon (3)

Guinea pig (3)

Horse (4)

Monkey (3)

Orangutan (3)

Pig (3)

Rabbit (1)

Zebrafish (1)

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Application

IHC (6)

IHC-P (4)

WB (24)

ELISA (12)

Peptide-ELISA (4)

RNAi (1)

Host

rabbit (23)

mouse (1)

goat (1)

Product Group

IHCPlus (1)

Isotype

IgG (15)

IgG2a,k (1)

Clonality

monoclonal mc (1)

polyclonal pc (24)

Clone

1C10 (1)

Format

96-Well Strip Plate (4)

APC Conjugated (1)

Azide-free (1)

Biotin Conjugated (2)

FITC Conjugated (2)

HRP Conjugated (2)

PE Conjugated (1)

Unconjugated (17)

Epitope

aa566-594 (7)

N-Terminus (4)

Internal (2)

aa484-603 (2)

aa241-290 (1)

aa451-485 (1)

aa590-603 (1)

Publications

No (33)

Sample Type

Plasma (2)

Serum (2)

Tag

GST (1)

GST, N-terminus (1)

Myc-DDK (Flag) (2)

Species

Human (3)

Source

293T Cells (1)

HEK 293 Cells (1)

Wheat Germ Extract (2)

Purification

Purified (1)

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Mouse MTM1 / Myotubularin (Sandwich ELISA) ELISA Kit - LS-F49624

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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MTM1 / Myotubularin Antibody (clone 1C10) LS-C133331

Antibody:

MTM1 / Myotubularin Mouse anti-Human Monoclonal (1C10) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, RNAi, WB

Format:

Unconjugated

Price:

100 µg/$423

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IHC-plus™ MTM1 / Myotubularin Antibody (aa590-603) LS-B15936

(4.0) Rating

Antibody:

MTM1 / Myotubularin Goat anti-Human Polyclonal (aa590-603) Antibody

Reactivity:

Rabbit, Bovine, Horse, Human

Applications:

IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µg/$460

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MTM1 / Myotubularin Antibody (aa241-290) LS-C199929

Antibody:

MTM1 / Myotubularin Rabbit anti-Human Polyclonal (aa241-290) Antibody

Reactivity:

Mouse, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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MTM1 / Myotubularin Antibody (aa484-603) LS-C377353

Antibody:

MTM1 / Myotubularin Rabbit anti-Human Polyclonal (aa484-603) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

Select

Human MTM1 / Myotubularin (Sandwich ELISA) ELISA Kit - LS-F49625

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

Select

MTM1 / Myotubularin Antibody LS-C666946

Antibody:

MTM1 / Myotubularin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$331

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MTM1 / Myotubularin Antibody (aa484-603) LS-C377350

Antibody:

MTM1 / Myotubularin Rabbit anti-Human Polyclonal (aa484-603) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

Select

MTM1 / Myotubularin Antibody LS-C809502

Antibody:

MTM1 / Myotubularin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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MTM1 / Myotubularin Antibody LS-C330873

Antibody:

MTM1 / Myotubularin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

Select

MTM1 / Myotubularin Antibody LS-C413754

Antibody:

MTM1 / Myotubularin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

0.1 mg/$394

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MTM1 / Myotubularin Antibody (aa566-594) LS-C323155

Antibody:

MTM1 / Myotubularin Rabbit anti-Human Polyclonal (aa566-594) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

MTM1 / Myotubularin Antibody (aa566-594, Biotin) LS-C263675

Antibody:

MTM1 / Myotubularin Rabbit anti-Human Polyclonal (aa566-594) (Biotin) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

MTM1 / Myotubularin Antibody (aa566-594, FITC) LS-C263676

Antibody:

MTM1 / Myotubularin Rabbit anti-Human Polyclonal (aa566-594) (FITC) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

MTM1 / Myotubularin Antibody (aa566-594, APC) LS-C263674

Antibody:

MTM1 / Myotubularin Rabbit anti-Human Polyclonal (aa566-594) (APC) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

MTM1 / Myotubularin Antibody (aa566-594, Azide-free, HRP) LS-C263677

Antibody:

MTM1 / Myotubularin Rabbit anti-Human Polyclonal (aa566-594) (Azide-free) (HRP) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

Select

MTM1 / Myotubularin Antibody (aa566-594, PE) LS-C263678

Antibody:

MTM1 / Myotubularin Rabbit anti-Human Polyclonal (aa566-594) (PE) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• HRP, Azide-free
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • HRP, Azide-free
  • PE

Select

MTM1 / Myotubularin Antibody (Internal) LS-C384726

Antibody:

MTM1 / Myotubularin Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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MTM1 / Myotubularin Antibody (N-Terminus) LS-C146521

Antibody:

MTM1 / Myotubularin Rabbit anti-Mouse Polyclonal (N-Terminus) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

MTM1 / Myotubularin Antibody (N-Terminus, HRP) LS-C461100

Antibody:

MTM1 / Myotubularin Rabbit anti-Mouse Polyclonal (N-Terminus) (HRP) Antibody

Reactivity:

Mouse, Guinea pig, Bovine, Pig, Horse, Orangutan, Gibbon, Human, Monkey

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP

• Unconjugated
• HRP

Select

MTM1 / Myotubularin Antibody (aa451-485) LS-C356619

Antibody:

MTM1 / Myotubularin Rabbit anti-Zebrafish Polyclonal (aa451-485) Antibody

Reactivity:

Zebrafish

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

400 µl/$393

Select

MTM1 / Myotubularin Antibody LS-C748566

Antibody:

MTM1 / Myotubularin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

Select

MTM1 / Myotubularin Antibody (Internal) LS-C352543

Antibody:

MTM1 / Myotubularin Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$299

Select

MTM1 / Myotubularin Antibody LS-C833129

Antibody:

MTM1 / Myotubularin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

Select

MTM1 / Myotubularin Antibody (aa566-594) LS-C98436

Antibody:

MTM1 / Myotubularin Rabbit anti-Human Polyclonal (aa566-594) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

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