MTHFD2

methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase

MTHFD2 encodes a nuclear-encoded mitochondrial bifunctional enzyme with methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities. The enzyme functions as a homodimer and is unique in its absolute requirement for magnesium and inorganic phosphate. Formation of the enzyme-magnesium complex allows binding of NAD. Alternative splicing results in two different transcripts, one protein-coding and the other not protein-coding. This gene has a pseudogene on chromosome 7.

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Proteins (8)

Type

Over-Expression Lysate (4)

Recombinant (4)

Target

MTHFD2 (8)

Publications

No (8)

Tag

6His-SUMO, N-terminus (1)

GST (1)

His (1)

Myc-DDK (Flag) (5)

Species

Cow (1)

Human (5)

Source

293T Cells (2)

E. coli (2)

HEK 293 Cells (3)

Wheat Germ Extract (1)

Purification

Purified (2)

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Human MTHFD2 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G66376

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

34.7 kDa

Price:

20 µg/$1,107

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Human MTHFD2 Protein (Recombinant GST) (Full Length) - LS-G32342

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

61.93 kDa

Price:

10 µg/$479; 25 µg/$670

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Human MTHFD2 Protein (Recombinant His) - LS-G3184

Source:

E. coli

Tag:

His

Price:

100 µg/$361; 500 µg/$739; 20 µg/$261

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Cow MTHFD2 Protein (Recombinant 6His-SUMO, N-terminus) (aa36-350) - LS-G57472

Source:

E. coli

Tag:

6His-SUMO, N-terminus

Price:

1 mg/$1,679; 100 µg/$598; 20 µg/$405

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MTHFD2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G100869

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

37.9 kDa

Price:

100 µg/$494

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Human MTHFD2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G77575

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

37.9 kDa

Price:

20 µg/$150

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Human MTHFD2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G77574

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

26.7 kDa

Price:

20 µg/$150

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MTHFD2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G120308

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

26.7 kDa

Price:

100 µg/$494

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