MTF2 / PCL2

metal response element binding transcription factor 2

Polycomb group (PcG) that specifically binds histone H3 trimethylated at 'Lys-36' (H3K36me3) and recruits the PRC2 complex. Acts by binding to H3K36me3, a mark for transcriptional activation, and recruiting the PRC2 complex, leading to enhance PRC2 H3K27me3 methylation activity. Regulates the transcriptional networks during embryonic stem cell self-renewal and differentiation. Promotes recruitment of the PRC2 complex to the inactive X chromosome in differentiating XX ES cells and PRC2 recruitment to target genes in undifferentiated ES cells. Required to repress Hox genes by enhancing H3K27me3 methylation of the PRC2 complex. In some conditions may act as an inhibitor of PRC2 activity: able to activate the CDKN2A gene and promote cellular senescence by suppressing the catalytic activity of the PRC2 complex locally. Binds to the metal-regulating-element (MRE) of MT1A gene promoter.

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Products

Antibodies (22)

Type

Primary (22)

Target

MTF2 / PCL2 (22)

Reactivity

Human (22)

Mouse (12)

Rat (10)

Bat (6)

Bovine (3)

Chimpanzee (6)

Dog (6)

Gibbon (6)

Guinea pig (3)

Horse (6)

Monkey (6)

Orangutan (6)

Pig (6)

Rabbit (6)

Xenopus (3)

Zebrafish (3)

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Application

IHC (2)

WB (22)

ELISA (9)

ICC (1)

IF (4)

IP (1)

Peptide-ELISA (1)

Host

rabbit (22)

Isotype

IgG (16)

Clonality

polyclonal pc (22)

Format

APC Conjugated (1)

Azide-free (1)

Biotin Conjugated (3)

FITC Conjugated (3)

HRP Conjugated (3)

PE Conjugated (1)

Unconjugated (11)

Epitope

aa289-317 (7)

aa26-75 (4)

aa359-408 (4)

Publications

No (22)

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MTF2 / PCL2 Antibody (aa359-408) LS-C109890

Antibody:

MTF2 / PCL2 Rabbit anti-Human Polyclonal (aa359-408) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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MTF2 / PCL2 Antibody (aa359-408, HRP) LS-C430885

Antibody:

MTF2 / PCL2 Rabbit anti-Human Polyclonal (aa359-408) (HRP) Antibody

Reactivity:

Rabbit, Mouse, Dog, Rat, Pig, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

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MTF2 / PCL2 Antibody (aa359-408, Biotin) LS-C430884

Antibody:

MTF2 / PCL2 Rabbit anti-Human Polyclonal (aa359-408) (Biotin) Antibody

Reactivity:

Rabbit, Mouse, Dog, Rat, Pig, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

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MTF2 / PCL2 Antibody (aa359-408, FITC) LS-C430886

Antibody:

MTF2 / PCL2 Rabbit anti-Human Polyclonal (aa359-408) (FITC) Antibody

Reactivity:

Rabbit, Mouse, Dog, Rat, Pig, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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MTF2 / PCL2 Antibody LS-C666939

Antibody:

MTF2 / PCL2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, IP, WB

Format:

Unconjugated

Price:

100 µg/$331

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MTF2 / PCL2 Antibody LS-C346218

Antibody:

MTF2 / PCL2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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MTF2 / PCL2 Antibody LS-C482767

Antibody:

MTF2 / PCL2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ICC, IF, WB

Format:

Unconjugated

Price:

50 µl/$286; 100 µl/$321; 200 µl/$386

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MTF2 / PCL2 Antibody LS-C768306

Antibody:

MTF2 / PCL2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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MTF2 / PCL2 Antibody (aa289-317) LS-C329853

Antibody:

MTF2 / PCL2 Rabbit anti-Human Polyclonal (aa289-317) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

MTF2 / PCL2 Antibody (aa289-317, Biotin) LS-C246532

Antibody:

MTF2 / PCL2 Rabbit anti-Human Polyclonal (aa289-317) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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MTF2 / PCL2 Antibody (aa289-317, FITC) LS-C246533

Antibody:

MTF2 / PCL2 Rabbit anti-Human Polyclonal (aa289-317) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

MTF2 / PCL2 Antibody (aa289-317, APC) LS-C246531

Antibody:

MTF2 / PCL2 Rabbit anti-Human Polyclonal (aa289-317) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

MTF2 / PCL2 Antibody (aa289-317, PE) LS-C246535

Antibody:

MTF2 / PCL2 Rabbit anti-Human Polyclonal (aa289-317) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

Select

MTF2 / PCL2 Antibody (aa289-317, Azide-free, HRP) LS-C248859

Antibody:

MTF2 / PCL2 Rabbit anti-Human Polyclonal (aa289-317) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• PE
• HRP, Azide-free

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • PE
  • HRP, Azide-free

Select

MTF2 / PCL2 Antibody LS-C401857

Antibody:

MTF2 / PCL2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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MTF2 / PCL2 Antibody LS-C405167

Antibody:

MTF2 / PCL2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

Select

MTF2 / PCL2 Antibody LS-C809007

Antibody:

MTF2 / PCL2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

MTF2 / PCL2 Antibody (aa289-317) LS-C158324

Antibody:

MTF2 / PCL2 Rabbit anti-Human Polyclonal (aa289-317) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

Select

MTF2 / PCL2 Antibody (aa26-75) LS-C30059

Antibody:

MTF2 / PCL2 Rabbit anti-Human Polyclonal (aa26-75) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

MTF2 / PCL2 Antibody (aa26-75, HRP) LS-C430888

Antibody:

MTF2 / PCL2 Rabbit anti-Human Polyclonal (aa26-75) (HRP) Antibody

Reactivity:

Xenopus, Zebrafish, Pig, Horse, Rabbit, Mouse, Dog, Guinea pig, Bovine, Bat, Rat, Gibbon, Orangutan, Human, Monkey, Chimpanzee

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

MTF2 / PCL2 Antibody (aa26-75, Biotin) LS-C430887

Antibody:

MTF2 / PCL2 Rabbit anti-Human Polyclonal (aa26-75) (Biotin) Antibody

Reactivity:

Xenopus, Zebrafish, Pig, Horse, Rabbit, Mouse, Dog, Guinea pig, Bovine, Bat, Rat, Gibbon, Orangutan, Human, Monkey, Chimpanzee

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

MTF2 / PCL2 Antibody (aa26-75, FITC) LS-C430889

Antibody:

MTF2 / PCL2 Rabbit anti-Human Polyclonal (aa26-75) (FITC) Antibody

Reactivity:

Xenopus, Zebrafish, Pig, Horse, Rabbit, Mouse, Dog, Guinea pig, Bovine, Bat, Rat, Gibbon, Orangutan, Human, Monkey, Chimpanzee

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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