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MTDH / Metadherin

metadherin

Downregulates SLC1A2/EAAT2 promoter activity when expressed ectopically. Activates the nuclear factor kappa-B (NF-kappa-B) transcription factor. Promotes anchorage-independent growth of immortalized melanocytes and astrocytes which is a key component in tumor cell expansion. Promotes lung metastasis and also has an effect on bone and brain metastasis, possibly by enhancing the seeding of tumor cells to the target organ endothelium. Induces chemoresistance.

Gene Name: metadherin
Synonyms: MTDH, 3D3, AEG1, AEG-1, Metadherin, LYRIC, Metastasis adhesion protein, Protein LYRIC
Target Sequences: Q86UE4 Q86UE4

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Products
Proteins (5)
Over-Expression Lysate (2)
Recombinant (3)
MTDH / Metadherin (5)
No (5)
GST (1)
His (1)
Myc-DDK (Flag) (3)
Human (3)
Mouse (1)
293T Cells (1)
E. coli (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (1)
Low endotoxin level (1)
MTDH / Metadherin Protein - Purified recombinant protein MTDH was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
63.7 kDa
20 µg/$1,107
MTDH / Metadherin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
63.7 kDa
20 µg/$150
MTDH / Metadherin Protein - 12.5% SDS-PAGE of human MTDH stained with Coomassie Blue
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Wheat Germ Extract
GST
90.2 kDa
2 µg/$439
MTDH / Metadherin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
63.7 kDa
100 µg/$494
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E. coli
249 AA
His
Less than 0.1 EU/µg protein (determined by LAL method).
27.5 kDa
10 mg/$4,268; 5 mg/$3,201; 1 mg/$1,868; 0.5 mg/$1,475; 200 µg/$1,103; 100 µg/$756; 50 µg/$531
Viewing 1-5 of 5 product results


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Products: Proteins


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).