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Major constituent of messenger ribonucleoprotein particles (mRNPs). Involved in the regulation of the stability and/or translation of germ cell mRNAs. Binds to Y-box consensus promoter element. Binds to full length mRNA with high affinity in a sequence-independent manner. Binds to short RNA sequences containing the consensus site 5'-UCCAUCA-3' with low affinity and limited sequence specificity. Its binding with maternal mRNAs is necessary for its cytoplasmic retention. May mark specific mRNAs (those transcribed from Y-box promoters) in the nucleus for cytoplasmic storage, thereby linking transcription and mRNA storage/translational delay.
Gene Name: | Y box binding protein 2 |
Synonyms: | YBX2, CONTRIN, CSDA3, DBPC, MSY2, Y-box-binding protein 2, Y box binding protein 2, DNA-binding protein C, MSY2 homolog |
Target Sequences: | NM_015982 NP_057066.2 Q9Y2T7 |
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