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MSX1
msh homeobox 1
MSX1 is a member of the muscle segment homeobox gene family. The encoded protein functions as a transcriptional repressor during embryogenesis through interactions with components of the core transcription complex and other homeoproteins. It may also have roles in limb-pattern formation, craniofacial development, particularly odontogenesis, and tumor growth inhibition. Mutations in this gene, which was once known as homeobox 7, have been associated with nonsyndromic cleft lip with or without cleft palate 5, Witkop syndrome, Wolf-Hirschom syndrome, and autosomoal dominant hypodontia.
| Gene Name: | msh homeobox 1 |
| Synonyms: | MSX1, ECTD3, Homeobox protein MSX-1, HOX7, Msh homeo box 1, Homeobox 7, OFC5, STHAG1, Msh homeobox homolog 1, Homeobox protein Hox-7, HYD1, Msh homeobox 1, Msh homeobox 1-like protein |
| Target Sequences: | NM_002448 NP_002439.2 P28360 |
Publications (2)
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