MSR1 / CD204

macrophage scavenger receptor 1

MSR1 / CD204 is a member of the class A macrophage scavenger receptors, which include three different types (1, 2, 3) generated by alternative splicing of this gene. These receptors or isoforms are macrophage-specific trimeric integral membrane glycoproteins and have been implicated in many macrophage-associated physiological and pathological processes including atherosclerosis, Alzheimer's disease, and host defense. The isoforms type 1 and type 2 are functional receptors and are able to mediate the endocytosis of modified low density lipoproteins (LDLs). The isoform type 3 does not internalize modified LDL (acetyl-LDL) despite having the domain shown to mediate this function in the types 1 and 2 isoforms. It has an altered intracellular processing and is trapped within the endoplasmic reticulum, making it unable to perform endocytosis. The isoform type 3 can inhibit the function of isoforms type 1 and type 2 when co-expressed, indicating a dominant negative effect and suggesting a mechanism for regulation of scavenger receptor activity in macrophages.

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Products

Proteins (14)

Type

Over-Expression Lysate (6)

Recombinant (8)

Target

MSR1 / CD204 (14)

Publications

No (14)

Tag

Fc (1)

GST, N-terminus (1)

GST, N-terminus + His, C-terminus (1)

His (3)

Myc-DDK (Flag) (8)

Species

Human (9)

Rat (2)

Source

293T Cells (3)

E. coli (2)

HEK 293 Cells (5)

Human Cells (3)

Wheat Germ Extract (1)

Purification

Purified (1)

Low Endotoxin Level

Low endotoxin level (3)

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Human MSR1 / CD204 Protein (Recombinant His) - LS-G3253

Source:

E. coli

Tag:

His

Price:

50 µg/$361; 250 µg/$739; 10 µg/$261

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Human MSR1 / CD204 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G66224

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

39.4 kDa

Price:

20 µg/$1,107

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Human MSR1 / CD204 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G66225

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

42.8 kDa

Price:

20 µg/$1,107

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Human MSR1 / CD204 Protein (Recombinant GST, N-terminus) (aa121-220) - LS-G59282

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human MSR1 / CD204 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G77203

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

49.6 kDa

Price:

20 µg/$150

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Human MSR1 / CD204 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G77202

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

39.4 kDa

Price:

20 µg/$150

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Human MSR1 / CD204 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G77204

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

42.8 kDa

Price:

20 µg/$150

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Human MSR1 / CD204 Protein (Recombinant His) (Lys77-Leu451) - LS-G97708

Source:

Human Cells

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

43 kDa

Price:

100 µg/$721

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MSR1 / CD204 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G107237

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

42.8 kDa

Price:

100 µg/$494

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MSR1 / CD204 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G102251

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

49.6 kDa

Price:

100 µg/$494

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Human MSR1 / CD204 Protein (Recombinant GST, N-terminus + His, C-terminus) - LS-G144813

Source:

E. coli

Tag:

GST, N-terminus + His, C-terminus

Molecular Weight:

75.6 kDa

Price:

50 µg/$419

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Rat MSR1 / CD204 Protein (Recombinant His) (Trp79-Ser454) - LS-G98446

Source:

Human Cells

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

43.1 kDa

Price:

100 µg/$721

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Rat MSR1 / CD204 Protein (Recombinant Fc) (Trp79-Ser454) - LS-G98447

Source:

Human Cells

Tag:

Fc

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

69.2 kDa

Price:

100 µg/$721

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MSR1 / CD204 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G117977

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

39.4 kDa

Price:

100 µg/$494

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