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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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We could not find product '(ID:86124)'. Here are some alternate products to this target that might be of interest to you.



MSLN / Mesothelin

mesothelin

This gene encodes a preproprotein that is cleaved into two products, megakaryocyte potentiating factor and mesothelin. Alternative splicing results in multiple transcript variants. Mesothelin is a cell surface differentiation antigen found in mesothelial cells, mesotheliomas and ovarian cancers. Although the function of mesothelin is unknown, it may play a role in cellular adhesion. Three transcript variants have been described. Their protein products were initially named megakaryocyte potentiating factor (MPF), mesothelin, and the soluble member(s) of the mesothelin/MPF family. MPF is a cytokine with megakaryocyte potentiating activity. Mesothelin null mutant mice show a normal phenotype suggesting that mesothelin function is not essential for growth or reproduction in mice (Bera et al., 2000).

Gene Name: mesothelin
Synonyms: MSLN, CAK1 antigen, MPF, SMRP, Mesothelin, CAK1
Target Sequences: NM_013404 NP_037536.2 Q13421

Publications (3)

1
New monoclonal antibodies to mesothelin useful for immunohistochemistry, fluorescence-activated cell sorting, Western blotting, and ELISA. Onda M, Willingham M, Nagata S, Bera TK, Beers R, Ho M, Hassan R, Kreitman RJ, Pastan I. Clinical cancer research : an official journal of the American Association for Cancer Research. 2005 11:5840-6. [PubMed:16115924] Related Antibodies: LS-C154007.
2
A practical approach to pancreatic cancer immunotherapy using resected tumor lysate vaccines processed to express a-gal epitopes. Furukawa K, Tanemura M, Miyoshi E, Eguchi H, Nagano H, Matsunami K, Nagaoka S, Yamada D, Asaoka T, Noda T, Wada H, Kawamoto K, Goto K, Taniyama K, Mori M, Doki Y. PloS one. 2017 12:e0184901. (IHC-P; Human) [Full Text Article] [PubMed:29077749] Related Antibodies: LS-C87690.
3
Pancreatic cancer therapy with combined mesothelin-redirected chimeric antigen receptor T cells and cytokine-armed oncolytic adenoviruses. Watanabe K, Luo Y, Da T, Guedan S, Ruella M, Scholler J, Keith B, Young RM, Engels B, Sorsa S, Siurala M, Havunen R, Tähtinen S, Hemminki A, June CH. JCI insight. 2018 April;3:pii: 99573. (Mouse) [Full Text Article] [PubMed:29618658] [PMC:PMC5928866] Related Antibodies: LS-C179484.

Viewing 1-25 of 106 items
MSLN / Mesothelin Antibody - Anti-MSLN / Mesothelin antibody IHC staining of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 15 ug/ml.
Select
Mouse Monoclonal [clone MN-1] (IgG2a) to Human MSLN / Mesothelin
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50µg   1mg/ml   $485.00
MSLN / Mesothelin Antibody - Human Lung, Mesothelium: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Rabbit Polyclonal (IgG) to Human MSLN / Mesothelin
Human
ELISA, IHC, IHC-P
Unconjugated
50µg   1mg/ml   $425.00
Select
Rabbit Polyclonal (IgG) to Human MSLN / Mesothelin
Human
ELISA
HRP Conjugated
50µg   $285.00; 100µg   0.42mg/ml   $385.00
MSLN / Mesothelin Antibody - Anti-Mesothelin Antibody - Immunohistochemistry. Immunohistochemistry using anti-mesothelin antibodies to detect mesothelin in PEFF human tissue sections treated by antigen retrieval methods. Anti-mesothelin primary antibodies were used to label these sections as follows: C, MAb MB; and D, MAb MN. Reprinted with permission fromClin. Cancer Res. 11(16):5840-6.
Select
Mouse Monoclonal [clone MB-G10] (IgG2a) to Human MSLN / Mesothelin
Human
ELISA, IHC, WB
Unconjugated
100µg   1mg/ml   $425.00
MSLN / Mesothelin Antibody - Formalin-fixed, paraffin-embedded human mesothelioma stained with peroxidase-conjugate and AEC chromogen. Note membrane staining of tumor cells.
Select
Mouse Monoclonal [clone 5B2] (IgG1) to Human MSLN / Mesothelin
Human
IHC, IHC-P
Unconjugated
0.1ml   $285.00
MSLN / Mesothelin Antibody
Select
Rat Monoclonal [clone B35] (IgG2a) to Mouse MSLN / Mesothelin
Mouse
Flo
Unconjugated
100µg   1mg/ml   $375.00
MSLN / Mesothelin Antibody - Mesothelin antibody IHC-paraffin. IHC(P): Mouse Lung Tissue.
Select
Rabbit Polyclonal to Mouse MSLN / Mesothelin
Mouse
IHC, IHC-P
Unconjugated
100µg   $355.00
MSLN / Mesothelin Antibody - MSLN / Mesothelin antibody Western blot of MCF7 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal (IgG) to Human MSLN / Mesothelin
Mouse, Guinea pig, Bovine, Pig, Human
WB
Unconjugated
100µl   0.5mg/ml   $385.00
MSLN / Mesothelin Antibody - MSLN / Mesothelin antibody Western blot of MCF7 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal (IgG) to Human MSLN / Mesothelin
Mouse, Guinea pig, Bovine, Pig, Gibbon, Human
WB
HRP Conjugated
100µl   0.65mg/ml   $405.00
MSLN / Mesothelin Antibody - Western Blot; Sample: Recombinant protein.
Select
Rabbit Polyclonal to Mouse MSLN / Mesothelin
Mouse
WB
Unconjugated
100µl   0.5mg/ml   $265.00; 200µl   0.5mg/ml   $305.00; 500µl   0.5mg/ml   $445.00; 1ml   0.5mg/ml   $545.00
MSLN / Mesothelin Antibody - Immunodetection Analysis: Representative blot from a previous lot. Lane 1, recombinant protein MSLN. The membrane blot was probed with antiMSLN primary antibody (1µg/ml). Proteins were visualized using a Donkey Anti-Rabbit secondary antibody conjugated to IRDye 800CW detection system. Arrows indicate cellular MSLN from human and mouse cells (34 kDa).
Select
Rabbit Polyclonal (IgG) to Human MSLN / Mesothelin
Human
ELISA, WB
Unconjugated, Preservative Free
20µg   $195.00; 100µg   $265.00; 200µg   $295.00; 500µg   $415.00
Select
Rabbit Polyclonal (IgG) to Mouse MSLN / Mesothelin
Mouse
ELISA, WB
Unconjugated
50µg   $285.00; 100µg   3.5mg/ml   $385.00
Select
Rabbit Polyclonal (IgG) to Mouse MSLN / Mesothelin
Mouse
ELISA, WB
HRP Conjugated
50µg   $285.00; 100µg   0.42mg/ml   $385.00
Select
Rabbit Polyclonal (IgG) to Mouse MSLN / Mesothelin
Mouse
ELISA, WB
Biotin Conjugated
50µg   $285.00; 100µg   0.25mg/ml   $385.00
Select
Rat Monoclonal (IgG2a) to Human MSLN / Mesothelin
Human
ELISA, Flo
Unconjugated
100µg   $680.00
Select
Mouse Monoclonal (IgG2b,k) to Human MSLN / Mesothelin
Human
ELISA, IP, WB
Biotin Conjugated
100µl   $710.00
MSLN / Mesothelin Antibody - MSLN / Mesothelin antibody Western blot of NCI-H226 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal (IgG) to Human MSLN / Mesothelin
Human
WB
Unconjugated
100µl   0.5mg/ml   $365.00
MSLN / Mesothelin Antibody
Select
Rabbit Polyclonal (IgG) to Mouse MSLN / Mesothelin
Mouse
IHC, IHC-P
Unconjugated
100µg   $435.00
MSLN / Mesothelin Antibody - Immunohistochemistry of paraffin-embedded Human lung cancer using MSLN Polyclonal Antibody at dilution of 1:40.
Select
Rabbit Polyclonal (IgG) to Human MSLN / Mesothelin
Human
ELISA, IHC
Unconjugated
20µl   0.5mg/ml   $205.00; 60µl   0.5mg/ml   $235.00; 120µl   0.5mg/ml   $295.00; 200µl   0.5mg/ml   $395.00
MSLN / Mesothelin Antibody - MSLN antibody (0.3 ug/ml) staining of Human Placenta lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Select
Goat Polyclonal to Human MSLN / Mesothelin
Human
Peptide-ELISA, WB
Unconjugated
100µg   0.5mg/ml   $405.00
Select
Mouse Monoclonal [clone K1] (IgG1) to Human MSLN / Mesothelin
Human
IHC-Fr
Unconjugated, Concentrated
1ml   $1,095.00
Select
Rabbit Polyclonal (IgG) to Human MSLN / Mesothelin
Human
WB
Biotin Conjugated
100µl   1mg/ml   $755.00
MSLN / Mesothelin Antibody - Mesothelin antibody IHC-paraffin: Human Lung Cancer Tissue.
Select
Rabbit Polyclonal to Human MSLN / Mesothelin
Human
ELISA, IHC, IHC-P, WB
Unconjugated
100µg   0.5mg/ml   $355.00
MSLN / Mesothelin Antibody - Immunohistochemistry of paraffin-embedded human lung tissue using antibody at 1:100 dilution.
Select
Rabbit Polyclonal (IgG) to Human MSLN / Mesothelin
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50µl   $285.00; 100µl   $385.00
MSLN / Mesothelin Antibody - Immunohistochemistry using the anti-mesothelin antibodies to detect mesothelin in PEFF human tissue sections treated by antigen retrieval methods. Anti-mesothelin primary antibodies were used to label these sections as follows: C, MAb MB; and D, MAb MN.
Select
Mouse Monoclonal [clone MB-G10] (IgG2a) to Human MSLN / Mesothelin
Human
ELISA, IHC, WB
Unconjugated
25µl   1mg/ml   $235.00

Viewing 1-25 of 106 items


If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).