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MSL3L1 / MSL3

male-specific lethal 3 homolog (Drosophila)

May be involved in chromatin remodeling and transcriptional regulation. May have a role in X inactivation. Component of the MSL complex which is responsible for the majority of histone H4 acetylation at 'Lys-16' which is implicated in the formation of higher-order chromatin structure. Specifically recognizes histone H4 monomethylated at 'Lys-20' (H4K20Me1) in a DNA-dependent manner and is proposed to be involved in chromosomal targeting of the MSL complex.

Gene Name: male-specific lethal 3 homolog (Drosophila)
Synonyms: MSL3, MSL3L1, MSL3-like 1, Male-specific lethal 3 homolog
Target Sequences: NM_006800 NP_006791.2 Q8N5Y2

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).