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Unfortunately, the antibody (ID:140164) is no longer available.

Below is a list of antibodies to the same protein target. You may also try your search again using the search box at the top of the page. Please contact us if you have any questions.



MSH6

mutS homolog 6

Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS alpha, which binds to DNA mismatches thereby initiating DNA repair. When bound, MutS alpha bends the DNA helix and shields approximately 20 base pairs, and recognizes single base mismatches and dinucleotide insertion-deletion loops (IDL) in the DNA. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis. ATP binding and hydrolysis play a pivotal role in mismatch repair functions. The ATPase activity associated with MutS alpha regulates binding similar to a molecular switch: mismatched DNA provokes ADP-->ATP exchange, resulting in a discernible conformational transition that converts MutS alpha into a sliding clamp capable of hydrolysis-independent diffusion along the DNA backbone. This transition is crucial for mismatch repair. MutS alpha may also play a role in DNA homologous recombination repair. Recruited on chromatin in G1 and early S phase via its PWWP domain that specifically binds trimethylated 'Lys-36' of histone H3 (H3K36me3): early recruitment to chromatin to be replicated allowing a quick identification of mismatch repair to initiate the DNA mismatch repair reaction.

Gene Name: mutS homolog 6
Synonyms: MSH6, GTBP, HSAP, GTMBP, MutS (E. coli) homolog 6, HMSH6, Sperm-associated protein, p160, G/T mismatch-binding protein, HNPCC5, MutS homolog 6 (E. coli), MutS-alpha 160 kDa subunit
Target Sequences: NM_000179 NP_000170.1 P52701
Featured Image

Featured MSH6 Antibody

LS-B5106 is a goat polyclonal antibody that LifeSpan has tested extensively in immunohistochemistry (IHC) and is an excellent antibody for use in formalin-fixed paraffin embedded tissues. Multiple tissues were immunolabeled and the results were interpreted by a LifeSpan pathologist. This image shows an example of staining in formalin-fixed paraffin embedded tissue. Learn more about our IHC Validation procedure. All LSBio antibodies are 100% guaranteed.


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Target Reactivity Applications Host Isotype Clonality Clone Format Epitope Publications Type
MSH6 Goat Polyclonal Unconjugated Human, Monkey, Mouse, Rat, Bat IHC-P aa2-14 No Primary
Anti-MSH6 Antibody (aa2-14) IHC-plus™ LS-B5106
Immunohistochemistry Image
Immunohistochemistry Image
Goat Polyclonal to Human MSH6
Human, Monkey, Mouse, Rat, Bat
IHC - Paraffin
Unconjugated
MSH6 Mouse IgG1 Monoclonal 5B11 Unconjugated Human IHC-P, WB, ELISA aa217-395 No Primary
Anti-MSH6 Antibody (aa217-395, clone 5B11) IHC-plus™ LS-B10739
Immunohistochemistry Image
Western blot Image
Mouse Monoclonal [clone 5B11] (IgG1) to Human MSH6
Human
IHC - Paraffin, Western blot, ELISA
Unconjugated
MSH6 Rabbit IgG Monoclonal SP93 Unconjugated Human IHC-P, WB Internal No Primary
Anti-MSH6 Antibody (Internal, clone SP93) LS-C210345
Immunohistochemistry Image
Immunohistochemistry Image
Rabbit Monoclonal [clone SP93] (IgG) to Human MSH6
Human
IHC - Paraffin, Western blot
Unconjugated
MSH6 Mouse IgG1 Monoclonal 3E1 Unconjugated Human IHC-P, ICC, IF, WB, Flo, ELISA No Primary
Anti-MSH6 Antibody (clone 3E1) LS-C169448
Immunohistochemistry Image
Immunohistochemistry Image
Mouse Monoclonal [clone 3E1] (IgG1) to Human MSH6
Human
IHC - Paraffin, ICC, Immunofluorescence, Western blot, Flow Cytometry, ELISA
Unconjugated
MSH6 Mouse IgG1 Monoclonal 44 Unconjugated Human IHC-P, IHC-Fr No Primary
Anti-MSH6 Antibody (clone 44) LS-C312106
Immunohistochemistry Image
Mouse Monoclonal [clone 44] (IgG1) to Human MSH6
Human
IHC - Paraffin, IHC - Frozen
Unconjugated
MSH6 Rabbit IgG Polyclonal Unconjugated Human, Mouse, Rat IHC, IF, WB No Primary
Anti-MSH6 Antibody LS-C332402
Immunohistochemistry Image
Immunofluorescence Image
Rabbit Polyclonal (IgG) to Human MSH6
Human, Mouse, Rat
IHC, Immunofluorescence, Western blot
Unconjugated
MSH6 Rabbit IgG Polyclonal Unconjugated Human, Mouse, Rat IHC, IF, WB No Primary
Anti-MSH6 Antibody LS-C331182
Immunohistochemistry Image
Immunofluorescence Image
Rabbit Polyclonal (IgG) to Human MSH6
Human, Mouse, Rat
IHC, Immunofluorescence, Western blot
Unconjugated
MSH6 Goat IgG Polyclonal Unconjugated Human IHC-P, IF, WB, IP, PLA aa350-400 No Primary
Anti-MSH6 Antibody (aa350-400) LS-C286964
Immunohistochemistry Image
Western blot Image
Goat Polyclonal (IgG) to Human MSH6
Human
IHC - Paraffin, Immunofluorescence, Western blot, Immunoprecipitation, Proximity Ligation Assay
Unconjugated
MSH6 Rabbit Polyclonal Unconjugated Human, Mouse IHC-P, IF, WB Glu371 No Primary
Anti-MSH6 Antibody (Glu371) LS-C176981
Immunohistochemistry Image
Western blot Image
Rabbit Polyclonal to Human MSH6
Human, Mouse
IHC - Paraffin, Immunofluorescence, Western blot
Unconjugated
MSH6 Goat IgG Polyclonal Unconjugated Human IHC-P, IF aa350-400 No Primary
Anti-MSH6 Antibody (aa350-400) LS-C286390
Immunohistochemistry Image
Goat Polyclonal (IgG) to Human MSH6
Human
IHC - Paraffin, Immunofluorescence
Unconjugated
MSH6 Rabbit Polyclonal Unconjugated Human IHC Internal No Primary
Anti-MSH6 Antibody (Internal) LS-C50530
Immunohistochemistry Image
Rabbit Polyclonal to Human MSH6
Human
IHC
Unconjugated
MSH6 Mouse IgG1,k Monoclonal SPM525 Unconjugated Human IHC-P Internal No Primary
Anti-MSH6 Antibody (Internal, clone SPM525) LS-C210528
Immunohistochemistry Image
Mouse Monoclonal [clone SPM525] (IgG1,k) to Human MSH6
Human
IHC - Paraffin
Unconjugated
MSH6 Rabbit IgG Polyclonal Biotin Conjugated Human IHC, IHC-P, ELISA aa1-400 No Primary
Anti-MSH6 Antibody (aa1-400, Biotin) LS-C370005
Immunohistochemistry Image
Immunohistochemistry Image
Rabbit Polyclonal (IgG) to Human MSH6
Human
IHC, IHC - Paraffin, ELISA
Biotin Conjugated
MSH6 Rabbit IgG Polyclonal HRP Conjugated Human IHC, IHC-P, ELISA aa1-400 No Primary
Anti-MSH6 Antibody (aa1-400, HRP) LS-C370002
Immunohistochemistry Image
Immunohistochemistry Image
Rabbit Polyclonal (IgG) to Human MSH6
Human
IHC, IHC - Paraffin, ELISA
HRP Conjugated
MSH6 Rabbit IgG Polyclonal FITC Conjugated Human IHC, IHC-P, ELISA aa1-400 No Primary
Anti-MSH6 Antibody (aa1-400, FITC) LS-C370001
Immunohistochemistry Image
Immunohistochemistry Image
Rabbit Polyclonal (IgG) to Human MSH6
Human
IHC, IHC - Paraffin, ELISA
FITC Conjugated
MSH6 Mouse IgG1 Monoclonal 44 Unconjugated, Ready-to-Use Human IHC-P, IHC-Fr No Primary
Anti-MSH6 Antibody (clone 44, Ready-to-Use) LS-C348526
Immunohistochemistry Image
Mouse Monoclonal [clone 44] (IgG1) to Human MSH6
Human
IHC - Paraffin, IHC - Frozen
Unconjugated, Ready-to-Use
MSH6 Rabbit IgG Polyclonal Unconjugated Human, Monkey, Mouse IHC, IF, WB, ELISA aa310-390 No Primary
Anti-MSH6 Antibody (aa310-390) LS-C383879
Western blot Image
Western blot Image
Rabbit Polyclonal (IgG) to Human MSH6
Human, Monkey, Mouse
IHC, Immunofluorescence, Western blot, ELISA
Unconjugated
MSH6 Rabbit Polyclonal Unconjugated Human, Monkey IHC-P, ICC, IF, WB Internal No Primary
Anti-MSH6 Antibody (Internal) LS-C352291
Immunohistochemistry Image
Immunofluorescence Image
Rabbit Polyclonal to Human MSH6
Human, Monkey
IHC - Paraffin, ICC, Immunofluorescence, Western blot
Unconjugated
MSH6 Rabbit IgG Polyclonal Unconjugated Human, Mouse IHC, WB, ELISA No Primary
Anti-MSH6 Antibody LS-C404147
Immunohistochemistry Image
Western blot Image
Rabbit Polyclonal (IgG) to Human MSH6
Human, Mouse
IHC, Western blot, ELISA
Unconjugated
MSH6 Rabbit IgG Polyclonal Unconjugated Human, Mouse IHC, WB, ELISA No Primary
Anti-MSH6 Antibody LS-C400893
Immunohistochemistry Image
Western blot Image
Rabbit Polyclonal (IgG) to Human MSH6
Human, Mouse
IHC, Western blot, ELISA
Unconjugated
MSH6 Rabbit IgG Polyclonal Unconjugated Human IHC-P, ELISA aa1-400 No Primary
Anti-MSH6 Antibody (aa1-400) LS-C369999
Immunohistochemistry Image
Immunohistochemistry Image
Rabbit Polyclonal (IgG) to Human MSH6
Human
IHC - Paraffin, ELISA
Unconjugated
MSH6 Mouse IgG1 Monoclonal Unconjugated Human, Mouse, Rat, Dog IHC-P No Primary
Anti-MSH6 Antibody LS-C72820
Mouse Monoclonal (IgG1) to Human MSH6
Human, Mouse, Rat, Dog
IHC - Paraffin
Unconjugated
MSH6 Mouse IgG1,k Monoclonal 1F2 Unconjugated Human IF, WB, ELISA No Primary
Anti-MSH6 Antibody (clone 1F2) LS-C197374
Immunofluorescence Image
Western blot Image
Mouse Monoclonal [clone 1F2] (IgG1,k) to Human MSH6
Human
Immunofluorescence, Western blot, ELISA
Unconjugated
MSH6 Rabbit IgG Polyclonal Unconjugated Human WB, IP, PLA C-Terminus No Primary
Anti-MSH6 Antibody (C-Terminus) LS-C286965
Western blot Image
Rabbit Polyclonal (IgG) to Human MSH6
Human
Western blot, Immunoprecipitation, Proximity Ligation Assay
Unconjugated
MSH6 Mouse IgG1 Monoclonal 3A10H7 Unconjugated Human WB, ELISA No Primary
Anti-MSH6 Antibody (clone 3A10H7) LS-C109105
Western blot Image
Mouse Monoclonal [clone 3A10H7] (IgG1) to Human MSH6
Human
Western blot, ELISA
Unconjugated
MSH6 Rabbit IgG Polyclonal Unconjugated Human, Mouse WB, ELISA aa341-390 No Primary
Anti-MSH6 Antibody (aa341-390) LS-C119578
Western blot Image
Rabbit Polyclonal (IgG) to Human MSH6
Human, Mouse
Western blot, ELISA
Unconjugated
MSH6 Rabbit IgG Polyclonal 15B Unconjugated Human, Mouse WB, ELISA Internal No Primary
Anti-MSH6 Antibody (Internal, clone 15B) LS-C191748
Rabbit Polyclonal [clone 15B] (IgG) to Human MSH6
Human, Mouse
Western blot, ELISA
Unconjugated
MSH6 Rabbit Polyclonal Unconjugated Human, Monkey, Mouse, Guinea pig WB aa251-300 No Primary
Anti-MSH6 Antibody (aa251-300) LS-C110632
Western blot Image
Rabbit Polyclonal to Human MSH6
Human, Monkey, Mouse, Guinea pig
Western blot
Unconjugated
MSH6 Mouse IgG1 Monoclonal Unconjugated Human WB, ELISA, GS No Primary
Anti-MSH6 Antibody LS-C43815
Mouse Monoclonal (IgG1) to Human MSH6
Human
Western blot, ELISA, Gel shift
Unconjugated
MSH6 Mouse IgG1 Monoclonal 44 Unconjugated Human, Mouse, Rat, Dog WB, IP No Primary
Anti-MSH6 Antibody (clone 44) LS-C95606
Mouse Monoclonal [clone 44] (IgG1) to Human MSH6
Human, Mouse, Rat, Dog
Western blot, Immunoprecipitation
Unconjugated
MSH6 Rabbit Polyclonal Biotin Conjugated Human, Gibbon, Monkey, Mouse, Guinea pig WB aa251-300 No Primary
Anti-MSH6 Antibody (aa251-300, Biotin) LS-C442019
Western blot Image
Rabbit Polyclonal to Human MSH6
Human, Gibbon, Monkey, Mouse, Guinea pig
Western blot
Biotin Conjugated
MSH6 Rabbit Polyclonal HRP Conjugated Human, Gibbon, Monkey, Mouse, Guinea pig WB aa251-300 No Primary
Anti-MSH6 Antibody (aa251-300, HRP) LS-C442020
Western blot Image
Rabbit Polyclonal to Human MSH6
Human, Gibbon, Monkey, Mouse, Guinea pig
Western blot
HRP Conjugated
MSH6 Rabbit Polyclonal FITC Conjugated Human, Gibbon, Monkey, Mouse, Guinea pig WB aa251-300 No Primary
Anti-MSH6 Antibody (aa251-300, FITC) LS-C442018
Western blot Image
Rabbit Polyclonal to Human MSH6
Human, Gibbon, Monkey, Mouse, Guinea pig
Western blot
FITC Conjugated
MSH6 Rabbit Polyclonal Unconjugated Human WB No Primary
Anti-MSH6 Antibody LS-C147004
Rabbit Polyclonal to Human MSH6
Human
Western blot
Unconjugated
MSH6 Mouse Monoclonal Unconjugated Human WB No Primary
Anti-MSH6 Antibody LS-C342045
Mouse Monoclonal to Human MSH6
Human
Western blot
Unconjugated
MSH6 Rabbit Polyclonal Unconjugated Human No Primary
Anti-MSH6 Antibody LS-C488358
Rabbit Polyclonal to Human MSH6
Human
Unconjugated
MSH6 Rabbit Polyclonal Unconjugated Human No Primary
Anti-MSH6 Antibody LS-C488357
Rabbit Polyclonal to Human MSH6
Human
Unconjugated
MSH6 Goat Polyclonal Unconjugated Human ICC, WB, IP Internal No Primary
Anti-MSH6 Antibody (Internal) LS-C72817
Goat Polyclonal to Human MSH6
Human
ICC, Western blot, Immunoprecipitation
Unconjugated
MSH6 Rabbit IgG Monoclonal Unconjugated Human, Monkey IF, WB C-Terminus No Primary
Anti-MSH6 Antibody (C-Terminus) LS-C191051
Rabbit Monoclonal (IgG) to Human MSH6
Human, Monkey
Immunofluorescence, Western blot
Unconjugated
MSH6 Mouse IgG1 Monoclonal Unconjugated Human ELISA, GS No Primary
Anti-MSH6 Antibody LS-C9101
Mouse Monoclonal (IgG1) to Human MSH6
Human
ELISA, Gel shift
Unconjugated
MSH6 Rabbit Polyclonal Unconjugated Human WB, IP Internal No Primary
Anti-MSH6 Antibody (Internal) LS-C72818
Rabbit Polyclonal to Human MSH6
Human
Western blot, Immunoprecipitation
Unconjugated
Target Corresponding Antibodies
MSH6
MSH6 Antibody Blocking Peptide - LS-E15211
LS-E15211
MSH6
LS-C110632
Type Target Tag Species Source Purified Biological Activity Known Endotoxin Level Animal-Free
Recombinant MSH6 GST Human E. coli
Human MSH6 Recombinant (GST) Protein - LS-G20142
E. coli Expression System
GST
Unpurified / Lyophilized
Recombinant MSH6 His + SUMO Human E. coli
Human MSH6 Recombinant (His + SUMO) Protein - LS-G20985
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image
E. coli Expression System
His + SUMO
Unpurified / Lyophilized

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).


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