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MSH5

mutS homolog 5

MSH5 is a member of the mutS family of proteins that are involved in DNA mismatch repair and meiotic recombination. This protein is similar to a Saccharomyces cerevisiae protein that participates in segregation fidelity and crossing-over events during meiosis. This protein plays a role in promoting ionizing radiation-induced apoptosis. This protein forms hetero-oligomers with another member of this family, mutS homolog 4. Polymorphisms in this gene have been linked to various human diseases, including IgA deficiency, common variable immunodeficiency, and premature ovarian failure. Alternative splicing results multiple transcript variants. Read-through transcription also exists between this gene and the downstream chromosome 6 open reading frame 26 (C6orf26) gene.

Gene Name: mutS homolog 5
Synonyms: MSH5, MutS homolog 5 (E. coli), HMSH5, MutS protein homolog 5, NG23, G7, MutS (E. coli) homolog 5, MUTSH5
Target Sequences: NM_002441 NP_002432.1 O43196

Publications (1)

1
FancJ (Brip1) loss-of-function allele results in spermatogonial cell depletion during embryogenesis and altered processing of crossover sites during meiotic prophase I in mice. Sun X, Brieño-Enríquez MA, Cornelius A, Modzelewski AJ, Maley TT, Campbell-Peterson KM, Holloway JK, Cohen PE. Chromosoma. 2016 June;125:237-52. (Human) [Full Text Article] [PubMed:26490168] [PMC:PMC5415080] Related Antibodies: LS-C101911.

☰ Filters
Antibodies (20)
Proteins (7)
Over-Expression Lysate (4)
Primary (20)
Recombinant (3)
MSH5 (27)
Human (20)
Mouse (5)
Rat (3)
Chicken (1)
Chimpanzee (6)
Horse (3)
Monkey (1)
Pig (3)
Xenopus (1)
IHC (1)
IHC-P (1)
WB (18)
ELISA (8)
IF (1)
Peptide-ELISA (1)
rabbit (18)
mouse (1)
goat (1)
Product Group
IHCPlus (1)
IgG (17)
IgG2a,k (1)
monoclonal mc (1)
polyclonal pc (19)
1C11 (1)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (1)
Preservative Free (1)
Unconjugated (9)
aa525-552 (7)
aa107-156 (4)
aa144-193 (4)
aa508-519 (1)
No (26)
Yes (1)
GST, N-terminus (1)
Myc-DDK (Flag) (6)
Human (5)
293T Cells (2)
HEK 293 Cells (4)
Wheat Germ Extract (1)
MSH5 Antibody - Anti-MSH5 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.
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MSH5 Goat anti-Human Polyclonal (aa508-519) Antibody
Xenopus, Chicken, Mouse, Human, Monkey
IHC, IHC-P, Peptide-ELISA
Unconjugated
50 µg/$485
MSH5 Antibody - MSH5 antibody Western blot of 721_B cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MSH5 Rabbit anti-Human Polyclonal (aa144-193) Antibody
Human
WB
Unconjugated
100 µl/$424
MSH5 Antibody - MSH5 antibody Western blot of 721_B cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MSH5 Rabbit anti-Human Polyclonal (aa144-193) (HRP) Antibody
Human, Chimpanzee
WB
HRP Conjugated
100 µl/$469
MSH5 Antibody - MSH5 antibody Western blot of 721_B cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MSH5 Rabbit anti-Human Polyclonal (aa144-193) (Biotin) Antibody
Human, Chimpanzee
WB
Biotin Conjugated
100 µl/$469
MSH5 Antibody - MSH5 antibody Western blot of 721_B cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MSH5 Rabbit anti-Human Polyclonal (aa144-193) (FITC) Antibody
Human, Chimpanzee
WB
FITC Conjugated
100 µl/$469
MSH5 Antibody - Western blot analysis of extracts of various cell lines, using MSH5 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 30s.
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MSH5 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
MSH5 Antibody - MSH5 Antibody western blot of HL-60 cell line lysates (35 ug/lane). The MSH5 antibody detected the MSH5 protein (arrow).
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MSH5 Rabbit anti-Human Polyclonal (aa525-552) Antibody
Human
WB
Unconjugated
400 µl/$393
MSH5 Antibody - Immunofluorescence of monoclonal antibody to MSH5 on HeLa cell . [antibody concentration 10 ug/ml]
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MSH5 Mouse anti-Human Monoclonal (1C11) Antibody
Human
ELISA, IF, WB
Unconjugated
100 µg/$423
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MSH5 Rabbit anti-Human Polyclonal (aa525-552) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
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MSH5 Rabbit anti-Human Polyclonal (aa525-552) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
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MSH5 Rabbit anti-Human Polyclonal (aa525-552) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
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MSH5 Rabbit anti-Human Polyclonal (aa525-552) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
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MSH5 Rabbit anti-Human Polyclonal (aa525-552) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
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MSH5 Rabbit anti-Human Polyclonal (aa525-552) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
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MSH5 Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
100 µg/$341
MSH5 Antibody - MSH5 antibody Western blot of HepG2 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MSH5 Rabbit anti-Human Polyclonal (aa107-156) Antibody
Human
WB
Unconjugated
100 µl/$424
MSH5 Antibody - MSH5 antibody Western blot of HepG2 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MSH5 Rabbit anti-Human Polyclonal (aa107-156) (HRP) Antibody
Mouse, Rat, Pig, Horse, Chimpanzee, Human
WB
HRP Conjugated
100 µl/$469
MSH5 Antibody - MSH5 antibody Western blot of HepG2 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MSH5 Rabbit anti-Human Polyclonal (aa107-156) (Biotin) Antibody
Mouse, Rat, Pig, Horse, Chimpanzee, Human
WB
Biotin Conjugated
100 µl/$469
MSH5 Antibody - MSH5 antibody Western blot of HepG2 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MSH5 Rabbit anti-Human Polyclonal (aa107-156) (FITC) Antibody
Mouse, Rat, Pig, Horse, Chimpanzee, Human
WB
FITC Conjugated
100 µl/$469
MSH5 Antibody - Anti-MSH5 rabbit polyclonal antibody at 1:500 dilution. Lane A: HL-60 Whole Cell Lysate. Lysates/proteins at 30 ug per lane. Secondary: Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution. Developed using the Odyssey technique. Performed under reducing conditions. Predicted band size: 93 kDa. Observed band size: 93 kDa.
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MSH5 Rabbit anti-Human Polyclonal (Preservative Free) Antibody
Human
WB
Unconjugated, Preservative Free
100 µl/$412
MSH5 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
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293T Cells
Myc-DDK (Flag)
92.7 kDa
20 µg/$150
MSH5 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
92.7 kDa
20 µg/$215
MSH5 Protein - Purified recombinant protein MSH5 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
92.7 kDa
20 µg/$1,107
MSH5 Protein - Purified recombinant protein MSH5 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
92.7 kDa
20 µg/$1,107
Viewing 1-25 of 27 product results



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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).