MS4A2 / FCERI

membrane-spanning 4-domains, subfamily A, member 2

The allergic response involves the binding of allergen to receptor-bound IgE followed by cell activation and the release of mediators responsible for the manifestations of allergy. The IgE-receptor, a tetramer composed of an alpha, beta, and 2 disulfide-linked gamma chains, is found on the surface of mast cells and basophils. This gene encodes the beta subunit of the high affinity IgE receptor which is a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This family member is localized to 11q12, among a cluster of membrane-spanning 4A gene family members. Alternative splicing results in multiple transcript variants encoding distinct proteins. Additional transcript variants have been described but require experimental validation.

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Products

Proteins (4)

Type

Over-Expression Lysate (2)

Recombinant (2)

Target

MS4A2 / FCERI (4)

Publications

No (4)

Tag

GST (1)

GST, N-terminus (1)

Myc-DDK (Flag) (2)

Species

Human (3)

Source

293T Cells (1)

HEK 293 Cells (1)

Wheat Germ Extract (2)

Purification

Purified (1)

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Human MS4A2 / FCERI Protein (Recombinant GST) (Full Length) - LS-G28447

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

52.9 kDa

Price:

10 µg/$479; 25 µg/$670

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MS4A2 / FCERI Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G98933

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

26.4 kDa

Price:

100 µg/$494

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Human MS4A2 / FCERI Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G76485

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

26.4 kDa

Price:

20 µg/$150

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Human MS4A2 / FCERI Protein (Recombinant GST, N-terminus) (aa1-59) - LS-G58540

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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