MRVI1

Murine Retrovirus Integration Site 1 Homolog

MRVI1 is similar to a putative mouse tumor suppressor gene (Mrvi1) that is frequently disrupted by mouse AIDS-related virus (MRV). The encoded protein, which is found in the membrane of the endoplasmic reticulum, is similar to Jaw1, a lymphoid-restricted protein whose expression is down-regulated during lymphoid differentiation. This protein is a substrate of cGMP-dependent kinase-1 (PKG1) that can function as a regulator of IP3-induced calcium release. Studies in mouse suggest that MRV integration at Mrvi1 induces myeloid leukemia by altering the expression of a gene important for myeloid cell growth and/or differentiation, and thus this gene may function as a myeloid leukemia tumor suppressor gene. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene, and alternative translation start sites, including a non-AUG (CUG) start site, are used.

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Products

Antibodies (4)

Proteins (3)

Type

Over-Expression Lysate (2)

Primary (4)

Recombinant (1)

Target

MRVI1 (7)

Reactivity

Human (4)

Mouse (3)

Bat (3)

Bovine (3)

Chimpanzee (3)

Dog (3)

Guinea pig (3)

Horse (3)

Monkey (3)

Pig (3)

Rabbit (3)

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Application

WB (4)

Host

rabbit (4)

Clonality

polyclonal pc (4)

Format

Biotin Conjugated (1)

FITC Conjugated (1)

HRP Conjugated (1)

Unconjugated (1)

Epitope

aa51-100 (4)

Publications

No (6)

Yes (1)

Tag

Myc-DDK (Flag) (3)

Species

Human (2)

Source

293T Cells (1)

HEK 293 Cells (2)

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MRVI1 Antibody (aa51-100) LS-C205780

(4.0) Rating

(1) Publication(s)

Antibody:

MRVI1 Rabbit anti-Human Polyclonal (aa51-100) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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MRVI1 Antibody (aa51-100, HRP) LS-C453588

Antibody:

MRVI1 Rabbit anti-Human Polyclonal (aa51-100) (HRP) Antibody

Reactivity:

Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Human, Monkey, Chimpanzee

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

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MRVI1 Antibody (aa51-100, Biotin) LS-C453586

Antibody:

MRVI1 Rabbit anti-Human Polyclonal (aa51-100) (Biotin) Antibody

Reactivity:

Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Human, Monkey, Chimpanzee

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

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MRVI1 Antibody (aa51-100, FITC) LS-C453587

Antibody:

MRVI1 Rabbit anti-Human Polyclonal (aa51-100) (FITC) Antibody

Reactivity:

Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Human, Monkey, Chimpanzee

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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Human MRVI1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G89471

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

97.7 kDa

Price:

20 µg/$215

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MRVI1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G119266

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

97.7 kDa

Price:

100 µg/$710

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Human MRVI1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G71313

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

97.7 kDa

Price:

20 µg/$1,107

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