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MRPL41 / PIG3 / BMRP
mitochondrial ribosomal protein L41
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the YmL27 ribosomal protein family.
| Gene Name: | mitochondrial ribosomal protein L41 |
| Synonyms: | MRPL41, BMRP, L41mt, MRP-L41, PIG3, MRP-L27, MRP-L27 homolog, Proliferation-inducing gene 3, RPML27 |
| Target Sequences: | NP_115866.1 Q8IXM3 |
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