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MRPL2

mitochondrial ribosomal protein L2

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the EcoL2 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 12q. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Gene Name: mitochondrial ribosomal protein L2
Synonyms: MRPL2, CGI-22, L2mt, RPML14, MRP-L2, MRP-L14
Target Sequences: NM_015950 NP_057034.2 Q5T653

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Products
Proteins (4)
Over-Expression Lysate (2)
Recombinant (2)
MRPL2 (4)
No (4)
His (1)
His-T7, N-terminus (1)
Myc-DDK (Flag) (2)
Human (2)
Mouse (1)
293T Cells (1)
E. coli (2)
HEK 293 Cells (1)
Purified (2)
MRPL2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
33.1 kDa
20 µg/$150
MRPL2 Protein - Recombinant Mitochondrial Ribosomal Protein L2 (MRPL2) by SDS-PAGE
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E. coli
His-T7, N-terminus
33.7kDa
10 µg/$267; 50 µg/$352; 200 µg/$702; 100 µg/$562; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,673; 2 mg/$1,900
MRPL2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
33.1 kDa
100 µg/$494
MRPL2 Protein
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E. coli
His
100 µg/$411; 500 µg/$985; 20 µg/$276
Viewing 1-4 of 4 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).