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MRC2 / Endo180

Mannose receptor, C type 2

May play a role as endocytotic lectin receptor displaying calcium-dependent lectin activity. Internalizes glycosylated ligands from the extracellular space for release in an endosomal compartment via clathrin-mediated endocytosis. May be involved in plasminogen activation system controlling the extracellular level of PLAUR/PLAU, and thus may regulate protease activity at the cell surface. May contribute to cellular uptake, remodeling and degradation of extracellular collagen matrices. May play a role during cancer progression as well as in other chronic tissue destructive diseases acting on collagen turnover. May participate in remodeling of extracellular matrix cooperating with the matrix metalloproteinases (MMPs).

Gene Name: Mannose receptor, C type 2
Synonyms: MRC2, CLEC13E, CD280, ENDO180, UPARAP
Target Sequences: NM_006039 NP_006030.2 Q9UBG0

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Proteins (5)
Over-Expression Lysate (2)
Recombinant (3)
MRC2 / Endo180 (5)
No (5)
GST, N-terminus (1)
His-T7 (1)
Myc-DDK (Flag) (3)
Human (4)
293T Cells (1)
E. coli (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (1)
MRC2 / Endo180 Protein - Recombinant  Mannose Receptor C Type 2 By SDS-PAGE
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E. coli
His-T7
56.6 kDa
10 µg/$284; 50 µg/$460; 100 µg/$735; 200 µg/$917; 1 mg/$2,037; 500 µg/$1,571; 5 mg/$3,207; 2 mg/$2,225
MRC2 / Endo180 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
MRC2 / Endo180 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
166.5 kDa
20 µg/$215
MRC2 / Endo180 Protein - Purified recombinant protein MRC2 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
166.5 kDa
20 µg/$1,107
MRC2 / Endo180 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
166.5 kDa
100 µg/$710
Viewing 1-5 of 5 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).