MORF4L1 / MRG15

mortality factor 4 like 1

Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also component of the mSin3A complex which acts to repress transcription by deacetylation of nucleosomal histones. Required for homologous recombination repair (HRR) and resistance to mitomycin C (MMC). Involved in the localization of PALB2, BRCA2 and RAD51, but not BRCA1, to DNA-damage foci.

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Products

Proteins (8)

Type

Over-Expression Lysate (4)

Recombinant (4)

Target

MORF4L1 / MRG15 (8)

Publications

No (8)

Tag

GST (1)

GST, N-terminus (1)

His (1)

Myc-DDK (Flag) (5)

Species

Human (6)

Source

293T Cells (2)

E. coli (1)

HEK 293 Cells (3)

Wheat Germ Extract (2)

Purification

Purified (2)

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Human MORF4L1 / MRG15 Protein (Recombinant GST, N-terminus) (aa1-100) - LS-G61684

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human MORF4L1 / MRG15 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G87469

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

37.1 kDa

Price:

20 µg/$150

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Human MORF4L1 / MRG15 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G87470

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

41.3 kDa

Price:

20 µg/$150

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Human MORF4L1 / MRG15 Protein (Recombinant GST) (Full Length) - LS-G32405

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

61.27 kDa

Price:

10 µg/$479; 25 µg/$670

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Human MORF4L1 / MRG15 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G70569

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

37.1 kDa

Price:

20 µg/$1,107

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MORF4L1 / MRG15 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G103018

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

41.3 kDa

Price:

100 µg/$494

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MORF4L1 / MRG15 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G100911

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

37.1 kDa

Price:

100 µg/$494

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Human MORF4L1 / MRG15 Protein (Recombinant His) - LS-G1711

Source:

E. coli

Tag:

His

Price:

100 µg/$361; 500 µg/$739; 20 µg/$261

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