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MOG

myelin oligodendrocyte glycoprotein

MOG is a membrane protein expressed on the oligodendrocyte cell surface and the outermost surface of myelin sheaths. Due to this localization, it is a primary target antigen involved in immune-mediated demyelination. This protein may be involved in completion and maintenance of the myelin sheath and in cell-cell communication. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene Name:	myelin oligodendrocyte glycoprotein
Family/Subfamily:	Immunoglobulin , not assigned-Immunoglobulin
Synonyms:	MOG, NRCLP7, MOGIG2, MOG alpha-5, MOG Ig-AluB
Target Sequences:	NM_002433 NP_002424.3 Q16653

Publications (1)

The formation of tau pore-like structures is prevalent and cell specific: possible implications for the disease phenotypes. Lasagna-Reeves CA, Sengupta U, Castillo-Carranza D, Gerson JE, Guerrero-Munoz M, Troncoso JC, Jackson GR, Kayed R. Acta neuropathologica communications. 2014 2:56. (IHC; Mouse) [Full Text Article] [PubMed:24887264] [PMC:PMC4231072]

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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