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MOCS3

molybdenum cofactor synthesis 3

Plays a central role in 2-thiolation of mcm5S2U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl-adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (-COSH) of their C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1 and MOCS2A. Subsequently, a transient disulfide bond is formed. Does not use thiosulfate as sulfur donor; NFS1 probably acting as a sulfur donor for thiocarboxylation reactions.

Gene Name: molybdenum cofactor synthesis 3
Synonyms: MOCS3, UBA4, DJ914P20.3, MPT synthase sulfurylase
Target Sequences: NM_014484 NP_055299.1 O95396

☰ Filters
Antibodies (26)
Proteins (4)
Over-Expression Lysate (2)
Primary (26)
Recombinant (2)
MOCS3 (30)
Human (21)
Mouse (9)
Rat (2)
IHC (4)
IHC-P (3)
WB (26)
ELISA (14)
ICC (1)
IF (2)
IP (1)
rabbit (19)
mouse (7)
IgG (18)
IgG2b,k (6)
monoclonal mc (6)
polyclonal pc (20)
1C5-E8 (1)
APC Conjugated (3)
Azide-free (1)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (3)
Unconjugated (11)
aa40-66 (7)
No (30)
GST (1)
Myc-DDK (Flag) (3)
Human (3)
293T Cells (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (1)
MOCS3 Antibody - Immunohistochemical analysis of MOCS3 staining in mouse kidney formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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MOCS3 Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
50 µl/$286; 100 µl/$321; 200 µl/$386
MOCS3 Antibody - Immunohistochemistry of paraffin-embedded human liver tissue at dilution 1:100
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MOCS3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
MOCS3 Antibody - Immunohistochemistry of paraffin-embedded human brain tissue at dilution 1:100
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MOCS3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
MOCS3 Antibody - Immunohistochemistry of paraffin-embedded mouse kidney tissue.
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MOCS3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
Select
MOCS3 Mouse anti-Human Monoclonal (1C5-E8) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$705
Select
MOCS3 Mouse anti-Human Monoclonal (HRP) Antibody
Human
ELISA, WB
HRP Conjugated
100 µl/$904
Select
MOCS3 Mouse anti-Human Monoclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
100 µl/$904
Select
MOCS3 Mouse anti-Human Monoclonal (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
100 µl/$904
Select
MOCS3 Mouse anti-Human Monoclonal (PE) Antibody
Human
ELISA, WB
PE Conjugated
100 µl/$904
Select
MOCS3 Mouse anti-Human Monoclonal (APC) Antibody
Human
ELISA, WB
APC Conjugated
100 µl/$904
Select
MOCS3 Rabbit anti-Human Polyclonal (aa40-66) Antibody
Mouse, Human
ELISA, WB
Unconjugated
200 µl/$734
Select
MOCS3 Rabbit anti-Mouse Polyclonal (aa40-66) (Biotin) Antibody
Mouse
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
MOCS3 Rabbit anti-Mouse Polyclonal (aa40-66) (FITC) Antibody
Mouse
ELISA, WB
FITC Conjugated
200 µl/$952
Select
MOCS3 Rabbit anti-Mouse Polyclonal (aa40-66) (APC) Antibody
Mouse
ELISA, WB
APC Conjugated
200 µl/$952
Select
MOCS3 Rabbit anti-Mouse Polyclonal (aa40-66) (PE) Antibody
Mouse
ELISA, WB
PE Conjugated
200 µl/$952
Select
MOCS3 Rabbit anti-Mouse Polyclonal (aa40-66) (Azide-free) (HRP) Antibody
Mouse
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
MOCS3 Rabbit anti-Human Polyclonal Antibody
Human
IP, WB
Unconjugated
100 µl/$749
Select
MOCS3 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µg/$749
Select
MOCS3 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$937
Select
MOCS3 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$937
Select
MOCS3 Rabbit anti-Human Polyclonal (PE) Antibody
Human
WB
PE Conjugated
100 µl/$937
Select
MOCS3 Rabbit anti-Human Polyclonal (APC) Antibody
Human
WB
APC Conjugated
100 µl/$937
MOCS3 Antibody - MOCS3 Antibody western blot of mouse heart tissue lysates (35 ug/lane). The MOCS3 antibody detected the MOCS3 protein (arrow).
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MOCS3 Rabbit anti-Human Polyclonal (aa40-66) Antibody
Mouse, Human
WB
Unconjugated
400 µl/$393
MOCS3 Antibody - Western blot analysis of extracts of various cell lines, using MOCS3 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 90s.
Select
MOCS3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
Select
MOCS3 Mouse anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µg/$705
Viewing 1-25 of 30 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).