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MNDA

myeloid cell nuclear differentiation antigen

The myeloid cell nuclear differentiation antigen (MNDA) is detected only in nuclei of cells of the granulocyte-monocyte lineage. A 200-amino acid region of human MNDA is strikingly similar to a region in the proteins encoded by a family of interferon-inducible mouse genes, designated Ifi-201, Ifi-202, and Ifi-203, that are not regulated in a cell- or tissue-specific fashion. The 1.8-kb MNDA mRNA, which contains an interferon-stimulated response element in the 5-prime untranslated region, was significantly upregulated in human monocytes exposed to interferon alpha. MNDA is located within 2,200 kb of FCER1A, APCS, CRP, and SPTA1. In its pattern of expression and/or regulation, MNDA resembles IFI16, suggesting that these genes participate in blood cell-specific responses to interferons.

Gene Name: myeloid cell nuclear differentiation antigen
Synonyms: MNDA, PYHIN3
Target Sequences: NM_002432 NP_002423.1 P41218

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Products
Antibodies (35)
Primary (35)
MNDA (35)
Human (35)
Chimpanzee (3)
IHC (15)
IHC-P (6)
WB (31)
Flo (7)
ELISA (14)
IF (2)
Peptide-ELISA (3)
rabbit (31)
mouse (4)
Product Group
IHCPlus (1)
IgG (21)
IgG2a (2)
IgG2a,k (1)
monoclonal mc (3)
polyclonal pc (32)
1H2 (1)
4H6 (2)
APC (1)
APC Conjugated (2)
Azide-free (1)
Biotin Conjugated (4)
Carrier-free (1)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (2)
Unconjugated (17)
aa189-405 (8)
aa26-53 (7)
C-Terminus (5)
aa37-321 (2)
350-430 aa, C-terminal (1)
Val406 (1)
aa357-406 (1)
aa358-407 (1)
No (35)
MNDA Antibody - MNDA Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human placenta tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
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MNDA Rabbit anti-Human Polyclonal (aa26-53) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
MNDA Antibody - Immunoperoxidase of monoclonal antibody to MNDA on formalin-fixed paraffin-embedded human kidney. [antibody concentration 3 ug/ml]
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MNDA Mouse anti-Human Monoclonal (1H2) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
100 µg/$423
MNDA Antibody - Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
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MNDA Mouse anti-Human Monoclonal (aa37-321) (4H6) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
MNDA Antibody - Immunohistochemical staining of paraffin-embedded Human Ovary tissue within the normal limits using anti-MNDA mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min,
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MNDA Mouse anti-Human Monoclonal (aa37-321) (Carrier-free) (4H6) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
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MNDA Mouse anti-Human Polyclonal Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µg/$705
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MNDA Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$351
MNDA Antibody - Immunohistochemistry of paraffin-embedded human skin tissue at dilution of 1:100
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MNDA Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
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MNDA Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
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MNDA Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
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MNDA Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
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MNDA Rabbit anti-Human Polyclonal (aa26-53) Antibody
Human
ELISA, Flo, IHC, WB
Unconjugated
200 µl/$734
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MNDA Rabbit anti-Human Polyclonal (aa26-53) (Biotin) Antibody
Human
ELISA, Flo, IHC, WB
Biotin Conjugated
200 µl/$952
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MNDA Rabbit anti-Human Polyclonal (aa26-53) (FITC) Antibody
Human
ELISA, Flo, IHC, WB
FITC Conjugated
200 µl/$952
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MNDA Rabbit anti-Human Polyclonal (aa26-53) (PE) Antibody
Human
ELISA, Flo, IHC, WB
PE Conjugated
200 µl/$952
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MNDA Rabbit anti-Human Polyclonal (aa26-53) (APC) Antibody
Human
ELISA, Flo, IHC, WB
APC Conjugated
200 µl/$952
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MNDA Rabbit anti-Human Polyclonal (aa26-53) (Azide-free) (HRP) Antibody
Human
ELISA, Flo, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
MNDA Antibody - Western blot of MNDA antibody
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MNDA Rabbit anti-Human Polyclonal (350-430 aa, C-terminal) Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
MNDA Antibody - Staining LOVO cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
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MNDA Rabbit anti-Human Polyclonal Antibody
Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
MNDA Antibody - Immunohistochemical analysis of MNDA staining in human lymph node formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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MNDA Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$299
MNDA Antibody - Western blot of MNDA (V406) pAb in extracts from LOVO cells.
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MNDA Rabbit anti-Human Polyclonal (Val406) Antibody
Human
IHC, WB
Unconjugated
50 µl/$321; 100 µl/$403
MNDA Antibody - Western blot analysis of extracts from LOVO cells, using MNDA antibody.
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MNDA Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$357
MNDA Antibody - Western blot analysis of lysates from LOVO cells, using MNDA Antibody. The lane on the right is blocked with the synthesized peptide.
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MNDA Rabbit anti-Human Polyclonal (aa358-407) Antibody
Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
MNDA Antibody - Western blot analysis of the lysates from 293 cells using MNDA antibody.
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MNDA Rabbit anti-Human Polyclonal (aa357-406) Antibody
Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
MNDA Antibody - Transfected 293T cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MNDA Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
MNDA Antibody - Western blot of recombinant MNDA.
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MNDA Rabbit anti-Human Polyclonal (aa189-405) Antibody
Human
WB
Unconjugated
100 µl/$303; 200 µl/$343; 500 µl/$476; 1 ml/$543; 2 ml/$715; 5 ml/$1,182
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).