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MMS19

MMS19 nucleotide excision repair homolog (S. cerevisiae)

Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins such as ERCC2/XPD, FANCJ and RTEL1, thereby playing a key role in nucleotide excision repair (NER) and RNA polymerase II (POL II) transcription. As part of the mitotic spindle-associated MMXD complex, plays a role in chromosome segregation, probably by facilitating iron-sulfur cluster assembly into ERCC2/XPD. Indirectly acts as a transcriptional coactivator of estrogen receptor (ER), via its role in iron-sulfur insertion into some component of the TFIIH-machinery.

Gene Name: MMS19 nucleotide excision repair homolog (S. cerevisiae)
Synonyms: MMS19, MET18, MMS19-like protein, MET18 homolog, MMS19L, HMMS19, Homolog of yeast MMS19
Target Sequences: NM_022362 NP_071757.4 Q96T76

☰ Filters
Antibodies (12)
Proteins (3)
Over-Expression Lysate (2)
Primary (12)
Recombinant (1)
MMS19 (15)
Human (12)
Mouse (2)
Rat (1)
IHC (2)
WB (12)
ELISA (8)
IF (2)
Peptide-ELISA (1)
rabbit (10)
mouse (2)
IgG (10)
IgG2a (1)
monoclonal mc (1)
polyclonal pc (11)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
PE Conjugated (1)
Unconjugated (7)
aa411-437 (7)
No (15)
GST (1)
Myc-DDK (Flag) (2)
Human (2)
293T Cells (1)
HEK 293 Cells (1)
Wheat Germ Extract (1)
Purified (1)
Select
MMS19 Mouse anti-Human Monoclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$351
MMS19 Antibody - 1:100 staining human breast carcinoma tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
Select
MMS19 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Select
MMS19 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$341
Select
MMS19 Rabbit anti-Human Polyclonal (aa411-437) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
Select
MMS19 Rabbit anti-Human Polyclonal (aa411-437) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
MMS19 Rabbit anti-Human Polyclonal (aa411-437) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
MMS19 Rabbit anti-Human Polyclonal (aa411-437) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
MMS19 Rabbit anti-Human Polyclonal (aa411-437) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
Select
MMS19 Rabbit anti-Human Polyclonal (aa411-437) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
MMS19 Mouse anti-Human Polyclonal Antibody
Human
IF, WB
Unconjugated
50 µg/$705
MMS19 Antibody - MMS19 Antibody western blot of human placenta tissue lysates (35 ug/lane). The MMS19 antibody detected the MMS19 protein (arrow).
Select
MMS19 Rabbit anti-Human Polyclonal (aa411-437) Antibody
Human
WB
Unconjugated
400 µl/$393
MMS19 Antibody - Western blot analysis of extracts of mouse thymus using MMS19 Polyclonal Antibody at dilution of 1:1000.
Select
MMS19 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
MMS19 Protein - 12.5% SDS-PAGE of human MMS19L stained with Coomassie Blue
Select
Wheat Germ Extract
GST
57.97 kDa
10 µg/$479; 25 µg/$670
MMS19 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
113.1 kDa
100 µg/$710
MMS19 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
113.1 kDa
20 µg/$215
Viewing 1-15 of 15 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).