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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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MMP8

matrix metallopeptidase 8 (neutrophil collagenase)

MMP8 is a member of the matrix metalloproteinase (MMP) family of proteins. These proteins are involved in the breakdown of extracellular matrix in embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Proteolysis at different sites on this protein results in multiple active forms of the enzyme with distinct N-termini. This protein functions in the degradation of type I, II and III collagens. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants.

Gene Name: matrix metallopeptidase 8 (neutrophil collagenase)
Family/Subfamily: Protease , Metallopeptidase M10A
Synonyms: MMP8, CLG1, HNC, Matrix metalloproteinase-8, MMP-8, Neutrophil collagenase, PMNL collagenase, PMNL-CL
Target Sequences: NM_002424 NP_002415.1 P22894

Filtered by: None
Type
Native (1)
Over-Expression Lysate (2)
Recombinant (10)
Target
MMP8 (13)
Tag
6His,N-terminus (1)
GST (1)
His (4)
His + T7 (1)
Myc + DDK (2)
Species
Human (10)
Mouse (1)
Rat (1)
Source
293T Cells (1)
E. coli (6)
HEK 293 Cells (1)
Human (1)
Human Cells (3)
Wheat Germ Extract (1)
Purification
Purified (10)
Low Endotoxin Level
Low endotoxin level (3)
Biologically Active
Biologically active (1)
Showing 1-13 of 13 results

Human MMP8 Protein (Recombinant) - LS-G17521
E. coli
None
Biologically active
1U  $255.00; 2.5U  $335.00; 10U  $950.00

Human MMP8 Protein (Recombinant GST) (Full Length) - LS-G29351
Wheat Germ Extract
GST
79.8 kDa
2µg  $385.00
12.5% SDS-PAGE of human MMP8 stained with Coomassie Blue

Human MMP8 Protein (Recombinant His) (Met1-Gly467) - LS-G97700
Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
52.6 kDa
10µg  $485.00; 20µg  $815.00

Human MMP8 Protein (Recombinant 6His,N-terminus) (Leu101-Gly467) - LS-G26516
E. coli
6His,N-terminus
42 kDa
10µg  $215.00; 50µg  $275.00; 100µg  $325.00; 250µg  $495.00
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image

Human MMP8 Protein (Native) - LS-G5488
Human
None
40-42 kDa
5µg  $355.00

Human MMP8 Protein (Recombinant) (Phe21-Gly467) - LS-G97698
Human Cells
None
Less than 1.0 EU/µg protein (determined by LAL method).
52 kDa
10µg  $485.00; 20µg  $815.00

Mouse MMP8 Protein (Recombinant) (Phe21-Ser465) - LS-G98220
Human Cells
None
Less than 1.0 EU/µg protein (determined by LAL method).
52 kDa
10µg  $485.00; 20µg  $815.00

Human MMP8 Protein (Recombinant His) - LS-G2757
E. coli
His
100µg 1mg/ml  $315.00; 0.5mg 1mg/ml  $695.00
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image

Human MMP8 Protein (Recombinant His) - LS-G17978
E. coli
His
5µg  $195.00; 20µg  $255.00; 1mg  $2,850.00

Human MMP8 Protein (Over-Expression Lysate Myc + DDK) (Full Length) - LS-G77689
293T Cells
Myc + DDK
53.41 kDa
20µg  $195.00

MMP8 Protein (Over-Expression Lysate Myc + DDK) (Full Length) - LS-G99750
HEK 293 Cells
Myc + DDK
53.41 kDa
100µg  $345.00

Human MMP8 Protein (Recombinant His) (aa101-467) - LS-G11561
E. coli
His
43.5 kDa
10µg  $325.00; 50µg  $605.00; 100µg  $830.00; 200µg  $1,215.00; 1mg  $3,120.00
Recombinant Matrix Metalloproteinase 8 By SDS-PAGE

Rat MMP8 Protein (Recombinant His + T7) (aa212-451) - LS-G11562
E. coli
His + T7
32.2 kDa
10µg  $285.00; 50µg  $475.00; 100µg  $650.00; 200µg  $950.00; 1mg  $2,430.00
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image
Recombinant Matrix Metalloproteinase 8 By SDS-PAGE
Showing 1-13 of 13 results

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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