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2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
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Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
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Tel: +1 (206) 374-1102
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order histories, retained contact details for faster checkout, review submissions, and special promotions.
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order histories, retained contact details for faster checkout, review submissions, and special promotions.
MMP8
matrix metallopeptidase 8 (neutrophil collagenase)
MMP8 is a member of the matrix metalloproteinase (MMP) family of proteins. These proteins are involved in the breakdown of extracellular matrix in embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Proteolysis at different sites on this protein results in multiple active forms of the enzyme with distinct N-termini. This protein functions in the degradation of type I, II and III collagens. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants.
| Gene Name: | matrix metallopeptidase 8 (neutrophil collagenase) |
| Family/Subfamily: | Protease , Metallopeptidase M10A |
| Synonyms: | MMP8, CLG1, HNC, Matrix metalloproteinase-8, MMP-8, Neutrophil collagenase, PMNL collagenase, PMNL-CL |
| Target Sequences: | NM_002424 NP_002415.1 P22894 |
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