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2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
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Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
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MMP10
matrix metallopeptidase 10 (stromelysin 2)
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans and fibronectin. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.
| Gene Name: | matrix metallopeptidase 10 (stromelysin 2) |
| Family/Subfamily: | Protease , Metallopeptidase M10A |
| Synonyms: | MMP10, Matrix metalloproteinase-10, SL-2, STMY2, Stromelysin 2, Stromelysin-2, MMP-10, Transin 2, Transin-2, Stromelysin2, Matrix metalloprotease 10 |
| Target Sequences: | NM_002425 NP_002416.1 P09238 |
Publications (2)
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