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MLNR/GPR38/Motilin Receptor
motilin receptor
GPR38, also called Motilin Receptor, mediates smooth muscle contraction and controls gastrointestinal motility by binding motilin. The antibiotic erythromycin-A also induces smooth muscle contraction when binding to the motilin receptor. Two variants are produced by alternative splicing. Associations exist between the motilin peptide and several gastrointestinal diseases (such as Crohn's disease, inflammatory bowel disease, and ulcerative colitis), suggesting that the motilin receptor may also be implicated in these diseases.
| Gene Name: | motilin receptor |
| Family/Subfamily: | GPCR , Motilin |
| Synonyms: | MLNR, G-protein coupled receptor 38, Motilin receptor, MTLR, MTLR1, G protein-coupled receptor 38, GPR38 |
| Target Sequences: | NM_001507 NP_001498.1 O43193 |
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