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MLH3

mutL homolog 3

MLH3 is a member of the MutL-homolog (MLH) family of DNA mismatch repair (MMR) genes. MLH genes are implicated in maintaining genomic integrity during DNA replication and after meiotic recombination. The protein encoded by this gene functions as a heterodimer with other family members. Somatic mutations in this gene frequently occur in tumors exhibiting microsatellite instability, and germline mutations have been linked to hereditary nonpolyposis colorectal cancer type 7 (HNPCC7). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined.

Gene Name: mutL homolog 3
Synonyms: MLH3, HNPCC7, MutL homolog 3 (E. coli), MutL protein homolog 3, MutL (E. coli) homolog 3
Target Sequences: NM_001040108 NP_001035197.1 Q9UHC1

☰ Filters
Antibodies (12)
Proteins (2)
ELISA Kits (1)
Over-Expression Lysate (2)
Primary (12)
Sandwich (1)
MLH3 (15)
Human (13)
Mouse (1)
Rat (1)
Chimpanzee (3)
Dog (3)
IHC (2)
WB (10)
ELISA (2)
IF (3)
Peptide-ELISA (4)
rabbit (11)
goat (1)
IgG (7)
polyclonal pc (12)
96-Well Strip Plate (1)
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
Unconjugated (9)
aa1188-1237 (4)
490-570 aa, Internal (1)
aa1416-1429 (1)
aa497-546 (1)
aa521-570 (1)
No (15)
Cell Lysates (1)
Tissue Homogenates (1)
Myc-DDK (Flag) (2)
Human (1)
293T Cells (1)
HEK 293 Cells (1)
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MLH3 Rabbit anti-Human Polyclonal (490-570 aa, Internal) Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
MLH3 Antibody - Western blot analysis of extracts of various cells.
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MLH3 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
MLH3 Antibody - 1:100 staining mouse lung tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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MLH3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
MLH3 Antibody - Western blot analysis of extracts from K562 cells and HT-29 cells, using MLH3 antibody.
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MLH3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$357
MLH3 Antibody - Goat Anti-MLH3 Antibody Immunofluorescence analysis of paraformaldehyde fixed HeLa cells, permeabilized with 0.15% Triton. Primary incubation 1hr (10ug/ml) followed by Alexa Fluor 488 secondary antibody (2ug/ml), showing nuclear staining. Actin filaments were stained with phalloidin (red) and the nuclear stain is DAPI (blue). Negative control: Unimmunized goat IgG (10ug/ml) followed by Alexa Fluor 488 secondary antibody (2ug/ml).
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MLH3 Goat anti-Human Polyclonal (aa1416-1429) Antibody
Human
IF, Peptide-ELISA
Unconjugated
100 µg/$503
MLH3 Antibody - Western blot analysis of lysates from K562 and HT-29 cells, using MLH3 Antibody. The lane on the right is blocked with the synthesized peptide.
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MLH3 Rabbit anti-Human Polyclonal (aa521-570) Antibody
Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
MLH3 Antibody - Western blot analysis of the lysates from Jurkat cells using MLH3 antibody.
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MLH3 Rabbit anti-Human Polyclonal (aa497-546) Antibody
Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
MLH3 Antibody - Immunofluorescence analysis of U2OS cells using MLH3 Polyclonal Antibody at dilution of 1:100.Blue: DAPI for nuclear staining.
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MLH3 Rabbit anti-Human Polyclonal Antibody
Human
IF
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
MLH3 Antibody - MLH3 antibody Western blot of 293T cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
MLH3 Rabbit anti-Human Polyclonal (aa1188-1237) Antibody
Human
WB
Unconjugated
100 µl/$424
MLH3 Antibody - MLH3 antibody Western blot of 293T cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MLH3 Rabbit anti-Human Polyclonal (aa1188-1237) (HRP) Antibody
Dog, Human, Chimpanzee
WB
HRP Conjugated
100 µl/$469
MLH3 Antibody - MLH3 antibody Western blot of 293T cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MLH3 Rabbit anti-Human Polyclonal (aa1188-1237) (Biotin) Antibody
Dog, Human, Chimpanzee
WB
Biotin Conjugated
100 µl/$469
MLH3 Antibody - MLH3 antibody Western blot of 293T cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
MLH3 Rabbit anti-Human Polyclonal (aa1188-1237) (FITC) Antibody
Dog, Human, Chimpanzee
WB
FITC Conjugated
100 µl/$469
MLH3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
160.8 kDa
100 µg/$710
MLH3 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$902
MLH3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
160.8 kDa
20 µg/$215
Viewing 1-15 of 15 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).