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MINPP1

multiple inositol-polyphosphate phosphatase 1

Acts as a phosphoinositide 5- and phosphoinositide 6-phosphatase and regulates cellular levels of inositol pentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6). Also acts as a 2,3-bisphosphoglycerate 3-phosphatase, by mediating the dephosphorylation of 2,3-bisphosphoglycerate (2,3-BPG) to produce phospho-D-glycerate without formation of 3-phosphoglycerate. May play a role in bone development (endochondral ossification).

Gene Name: multiple inositol-polyphosphate phosphatase 1
Synonyms: MINPP1, 2,3-BPG phosphatase, Ins(1,3,4,5)P(4) 3-phosphatase, MIPP, MINPP2, HIPER1
Target Sequences: NM_004897 NP_004888.2 Q9UNW1

Publications (1)

1
High-phytate/low-calcium diet is a risk factor for crystal nephropathies, renal phosphate wasting, and bone loss. Ok-Hee Kim, Carmen J Booth, Han Seok Choi, Jinwook Lee, Jinku Kang, June Hur, Woo Jin Jung, Yun-Shin Jung, Hyung Jin Choi, Hyeonjin Kim, Joong-Hyuck Auh, Jung-Wan Kim, Ji-Young Cha, Young Jae Lee, Cheol Soon Lee, Cheolsoo Choi, Yun Jae Jung, Jun-Young Yang, Seung-Soon Im, Dae Ho Lee, Sun Wook Cho, Young-Bum Kim, Kyong Soo Park, Young Joo Park, Byung-Chul Oh. eLife. 2020 Apr;9:e52709. [Full Text Article] [PubMed:32271147] [PMC:PMC7145417] Related Antibodies: LS-C368910.

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MINPP1 ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
0.78 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
MINPP1 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
MINPP1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).