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MINPP1

multiple inositol-polyphosphate phosphatase 1

Acts as a phosphoinositide 5- and phosphoinositide 6-phosphatase and regulates cellular levels of inositol pentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6). Also acts as a 2,3-bisphosphoglycerate 3-phosphatase, by mediating the dephosphorylation of 2,3-bisphosphoglycerate (2,3-BPG) to produce phospho-D-glycerate without formation of 3-phosphoglycerate. May play a role in bone development (endochondral ossification).

Gene Name: multiple inositol-polyphosphate phosphatase 1
Synonyms: MINPP1, 2,3-BPG phosphatase, Ins(1,3,4,5)P(4) 3-phosphatase, MIPP, MINPP2, HIPER1
Target Sequences: NM_004897 NP_004888.2 Q9UNW1

Publications (1)

1
High-phytate/low-calcium diet is a risk factor for crystal nephropathies, renal phosphate wasting, and bone loss. Ok-Hee Kim, Carmen J Booth, Han Seok Choi, Jinwook Lee, Jinku Kang, June Hur, Woo Jin Jung, Yun-Shin Jung, Hyung Jin Choi, Hyeonjin Kim, Joong-Hyuck Auh, Jung-Wan Kim, Ji-Young Cha, Young Jae Lee, Cheol Soon Lee, Cheolsoo Choi, Yun Jae Jung, Jun-Young Yang, Seung-Soon Im, Dae Ho Lee, Sun Wook Cho, Young-Bum Kim, Kyong Soo Park, Young Joo Park, Byung-Chul Oh. eLife. 2020 Apr;9:e52709. [Full Text Article] [PubMed:32271147] [PMC:PMC7145417] Related Antibodies: LS-C368910.

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Products
Antibodies (39)
Primary (39)
MINPP1 (39)
Human (32)
Mouse (7)
Rat (14)
Chimpanzee (3)
Monkey (3)
Orangutan (3)
IHC (15)
IHC-P (7)
WB (28)
Flo (14)
ELISA (25)
IF (3)
Peptide-ELISA (3)
rabbit (37)
mouse (2)
IgG (30)
IgG1 (2)
monoclonal mc (2)
polyclonal pc (37)
OTI1B2 (2)
APC Conjugated (2)
Azide-free (2)
Biotin Conjugated (6)
Carrier-free (1)
FITC Conjugated (6)
HRP Conjugated (6)
PE Conjugated (2)
Unconjugated (17)
aa28-55 (7)
aa31-481 (7)
aa370-398 (7)
aa31-487 (4)
aa409-458 (4)
300-380 aa, Internal (1)
Internal (1)
aa246-487 (1)
aa311-360 (1)
aa328-377 (1)
No (38)
Yes (1)
MINPP1 Antibody - Immunohistochemical analysis of MINPP1 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected with HRP and DAB as chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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MINPP1 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
30 µl/$255; 100 µl/$299; 200 µl/$351
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MINPP1 Rabbit anti-Human Polyclonal (aa370-398) Antibody
Human
ELISA, Flo, WB
Unconjugated
200 µl/$734
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MINPP1 Rabbit anti-Human Polyclonal (aa370-398) (Biotin) Antibody
Human
ELISA, Flo, WB
Biotin Conjugated
200 µl/$952
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MINPP1 Rabbit anti-Human Polyclonal (aa370-398) (FITC) Antibody
Human
ELISA, Flo, WB
FITC Conjugated
200 µl/$952
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MINPP1 Rabbit anti-Human Polyclonal (aa370-398) (Azide-free) (HRP) Antibody
Human
ELISA, Flo, WB
HRP Conjugated, Azide-free
200 µl/$952
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MINPP1 Rabbit anti-Human Polyclonal (aa370-398) (PE) Antibody
Human
ELISA, Flo, WB
PE Conjugated
200 µl/$952
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MINPP1 Rabbit anti-Human Polyclonal (aa370-398) (APC) Antibody
Human
ELISA, Flo, WB
APC Conjugated
200 µl/$952
MINPP1 Antibody - IHC of paraffin-embedded DLD-1 xenograft using MIPP antibody at 1:500 dilution.
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MINPP1 Rabbit anti-Human Polyclonal (aa246-487) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$450
MINPP1 Antibody - MINPP1 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human hepatocarcinoma followed by peroxidase-conjugated secondary antibody and DAB staining.
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MINPP1 Rabbit anti-Human Polyclonal (aa28-55) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
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MINPP1 Rabbit anti-Human Polyclonal (aa28-55) Antibody
Human
ELISA, Flo, IHC, WB
Unconjugated
200 µl/$734
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MINPP1 Rabbit anti-Human Polyclonal (aa28-55) (Biotin) Antibody
Human
ELISA, Flo, IHC, WB
Biotin Conjugated
200 µl/$952
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MINPP1 Rabbit anti-Human Polyclonal (aa28-55) (FITC) Antibody
Human
ELISA, Flo, IHC, WB
FITC Conjugated
200 µl/$952
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MINPP1 Rabbit anti-Human Polyclonal (aa28-55) (APC) Antibody
Human
ELISA, Flo, IHC, WB
APC Conjugated
200 µl/$952
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MINPP1 Rabbit anti-Human Polyclonal (aa28-55) (Azide-free) (HRP) Antibody
Human
ELISA, Flo, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
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MINPP1 Rabbit anti-Human Polyclonal (aa28-55) (PE) Antibody
Human
ELISA, Flo, IHC, WB
PE Conjugated
200 µl/$952
MINPP1 Antibody - Western blot of MIPP antibody
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MINPP1 Rabbit anti-Human Polyclonal (300-380 aa, Internal) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
MINPP1 Antibody - Immunohistochemistry of paraffin-embedded human placenta tissue using antibody at 1:100 dilution.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MINPP1 Rabbit anti-Human Polyclonal (aa31-487) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
MINPP1 Antibody - Immunohistochemistry of paraffin-embedded human placenta tissue using antibody at 1:100 dilution.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MINPP1 Rabbit anti-Human Polyclonal (aa31-487) (HRP) Antibody
Human
ELISA, IHC, IHC-P
HRP Conjugated
50 µg/$294; 100 µg/$360
MINPP1 Antibody - Immunohistochemistry of paraffin-embedded human placenta tissue using antibody at 1:100 dilution.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MINPP1 Rabbit anti-Human Polyclonal (aa31-487) (Biotin) Antibody
Human
ELISA, IHC, IHC-P
Biotin Conjugated
50 µg/$294; 100 µg/$360
MINPP1 Antibody - Immunohistochemistry of paraffin-embedded human placenta tissue using antibody at 1:100 dilution.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MINPP1 Rabbit anti-Human Polyclonal (aa31-487) (FITC) Antibody
Human
ELISA, IHC, IHC-P
FITC Conjugated
50 µg/$294; 100 µg/$360
MINPP1 Antibody - Staining 293 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody, diluted at 1/600, was used as secondary antibody.
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MINPP1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
MINPP1 Antibody - Anti-MINPP1 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY MINPP1.
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MINPP1 Mouse anti-Human Monoclonal (OTI1B2) Antibody
Human
IF, WB
Unconjugated
100 µl/$434
MINPP1 Antibody - Anti-MINPP1 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY MINPP1.
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MINPP1 Mouse anti-Human Monoclonal (Carrier-free) (OTI1B2) Antibody
Human
IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
MINPP1 Antibody - MINPP1 Antibody western blot of NCI-H460 cell line lysates (35 ug/lane). The MINPP1 antibody detected the MINPP1 protein (arrow).
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MINPP1 Rabbit anti-Human Polyclonal (aa370-398) Antibody
Human
Flo, WB
Unconjugated
400 µl/$393
MINPP1 Antibody - Western blot analysis of extracts from 293 cells, using MINPP1 antibody.
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MINPP1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).